Protein serine and threonine phosphatase
Protein Ser/Thr phosphatases are a group of enzymes that catalyze the removal of phosphate groups from serine and/or threonine residues by hydrolysis of phosphoric acid monoesters. They oppose the action of kinases and phosphorylases and are involved in signal transduction.
Products for Protein serine and threonine phosphatase - Page 2
- Cat.No. Product Name Information/Activity
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BCC2464
Okadaic acid
Okadaic acid is extracted from black sponges of the genus Halichondria. Okadaic acid is a non-comepetitive, selective and reversible serine/threonine-specific protein phosphatases 1 (PP1), PP2A and PP3 inhibitor with IC50s of 10-15 nM, 0.5 nM and 4 nM, respectively. Okadaic acid eliminate metazoan symbionts/parasites by apoptosis.
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BCC2465
Sal 003
Sal003 is a potent and cell-permeable eIF-2α phosphatase inhibitor.
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BCC4843
Salubrinal
Salubrinal is a selective inhibitor of eIF2α dephosphorylation and inhibits ER stress-mediated apoptosis with EC50 of ~15 μM in a cell-free assay.
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BCC6481
Sanguinarine chloride
Sanguinarine chloride, a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.
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BCC7320
Tautomycetin
119757-73-2
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BCC2458
Ceramide
Ser/Thr protein phosphatase activator
