5-HT7 Receptor

Serotonin 5-HT7 receptors are located primarily in the thalamus, hypothalamus and hippocampus. The function of these receptors includes the regulation of circadian rhythms, thermoregulation, learning and memory and smooth muscle relaxation.

Products for 5-HT7 Receptor

  1. Cat.No. Product Name Information/Activity
  2. BCC7218 AS 19 AS19 is a potent, selective 5-HT7 receptor agonist with an IC50 value of 0.83 nM and a Ki of 0.6 nM. AS19 is selective for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Kis = 89.7 nM, 490 nM, 6.6 nM and 98.5 nM, respectively). AS19 enhances memory consolidation and reverses Scopolamine- or Dizocilpine-induced amnesia. AS 19 chemical structure
  3. BCC7517 LP 12 hydrochloride 1185136-22-4 LP 12 hydrochloride chemical structure
  4. BCC7399 LP 44 824958-12-5 LP 44 chemical structure
  5. BCC7990 DR 4485 hydrochloride 402942-53-4 DR 4485 hydrochloride chemical structure
  6. BCC7101 LY 215840 137328-52-0 LY 215840 chemical structure
  7. BCC5937 SB 258719 hydrochloride 1217674-10-6 SB 258719 hydrochloride chemical structure
  8. BCC5056 SB269970 HCl SB269970 hydrochloride (SB-269970A) is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with the pKi of 8.3, exhibits >50-fold selectivity against other receptors. SB269970 HCl chemical structure
  9. BCC6652 5-Carboxamidotryptamine maleate 74885-72-6 5-Carboxamidotryptamine maleate chemical structure
  10. BCC6681 8-Hydroxy-DPAT hydrobromide 76135-31-4 8-Hydroxy-DPAT hydrobromide chemical structure
  11. BCC6266 LP 20 hydrochloride 1386928-34-2 LP 20 hydrochloride chemical structure

Items 1 to 10 of 11 total