Fatty Acid Amide Hydrolase
Fatty acid amide hydrolase, (FAAH, Oleamide hydrolase, Anandamide amidohydrolase), is an integral membrane protein that hydrolyzes bioactive amides, including anandamide, to free fatty acid and ethanolamine. FAAH belongs to the serine hydrolase enzyme family.
Products for Fatty Acid Amide Hydrolase
- Cat.No. Product Name Information/Activity
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BCC7075
AACOCF3
Phospholipase A<sub>2</sub> inhibitor
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BCC7675
AM 1172
FAAH inhibitor; also anandamide uptake inhibitor and CB receptor partial agonist
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BCC7500
Arachidonyl serotonin
187947-37-1
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BCC2315
JNJ-1661010
JNJ-1661010 (Takeda-25) a potent and selective fatty acid amide hydrolase (FAAH) inhibitor with IC50s of 34 and 33 nM for rat FAAH and human FAAH, respectively. JNJ-1661010 can cross the blood-brain barrier and used as broad-spectrum analgesics.
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BCC7966
JZL 195
JZL195 is a selective and efficacious dual fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) inhibitor with IC50s of 2 and 4 nM, respectively.
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BCC1718
LY2183240
LY2183240 is a novel and highly potent blocker of anandamide uptake (IC50 = 270 pM).
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BCC7187
Palmitoylisopropylamide
189939-61-5
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BCC2326
PF-3845
PF-3845 is a selective fatty acid amide hydrolase (FAAH) inhibitor (Ki = 0.23 μM); showing negligible activity against FAAH2.
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BCC7641
PF 750
PF 750 is a selective and covalent fatty acid amide hydrolase (FAAH) inhibitor, with IC50s varied from 16.2-595 nM in different pre-incubation times. Covalently modifies the enzyme’s active site serine nucleophile.
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BCC6289
SA 47
SA 47 is a selective and potent inhibitor of fatty acid amide hydrolase (FAAH) and carbamate.
