Adrenergic α1 Receptor
Adrenergic α 1 receptors (α 1-adrenoceptors) are members of the adrenergic receptor group of G-protein-coupled receptors that also includes α 2A, α 2B, α 2C, β 1, β 2 and β 3. The adrenergic α 1 receptors are further divided into three subtypes: α 1A, α 1B and α 1D receptors.
Products for Adrenergic α1 Receptor
- Cat.No. Product Name Information/Activity
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BCC6912
A 61603 hydrobromide
107756-30-9
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BCC6833
Cirazoline hydrochloride
Cirazoline hydrochloride (LD 3098 hydrochloride) is a potent competitive full α1A-adrenergic receptor (α1A-AR) agonist (Ki=120 nM) and only a partial agonist at α1B-AR (Ki= 960 nM) and α1D-AR (Ki=660 nM).
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BCC4333
Oxymetazoline HCl
2315-02-8
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BCC4335
Phenylephrine HCl
(R)-(-)-Phenylephrine hydrochloride is a selective α1-adrenoceptor agonist with pKis of 5.86, 4.87 and 4.70 for α1D, α1B and α1A receptors respectively.
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BCC2494
Alfuzosin HCl
Alfuzosin hydrochloride is an α1 adrenergic receptor antagonist used to treat benign prostatic hyperplasia (BPH).
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BCC5063
BMY 7378
5-HT<sub>1A</sub> partial agonist,BMY 7378 is a multi-targeted inhibitor of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2, respectively, and acts as a mixed agonist and antagonist for 5-HT1A receptor with pKi of 8.3.
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BCC4324
Carvedilol
Carvedilol (BM 14190) is a non-selective β/α-1 blocker. Carvedilol inhibits lipid peroxidation in a dose-dependent manner with an IC50 of 5 μM. Carvedilol is a multiple action antihypertensive agent with potential use in angina and congestive heart failure. Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome.
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BCC1257
Doxazosin Mesylate
Doxazosin mesylate (UK 33274) is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors.
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BCC6683
HEAT hydrochloride
30007-39-7
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BCC6688
Ifenprodil hemitartrate
23210-56-2
