Products for
Others
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BCC7788
CCMI
CCMI is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs. CCMI has potential in CNS diseases with cognitive dysfunction.
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BCC7535
NS 1738
NS 1738 (NSC 213859) is a novel positive allosteric modulator of the α7 nAChR, with respect to positive modulation of α7 nAChR (EC50=3.4 μM in oocyte experiments).
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BCC4581
PNU-120596
PNU-120596 (NSC 216666 ) is a potent and selective positive allosteric α7 nAChR modulator with an EC50 of 0.2 μM.
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BCC7896
TQS
353483-92-8
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BCC7564
FR 236924
DCP-LA (FR236924), a linoleic acid derivative, selectively and directly activates PKCε.
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BCC5756
Noladin ether
222723-55-9
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BCC6827
Oleamide
Oleamide is an endogenous fatty acid amide which can be synthesized de novo in the mammalian nervous system, and has been detected in human plasma.
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BCC4412
AM251
AM251 is a selective cannabinoid 1 (CB1) receptor antagonist with an IC50 of 8 nM, also acts as a potent GPR55 agonist with an EC50 of 39 nM.
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BCC6944
AM 281
Potent, selective CB<sub>1</sub> antagonist/inverse agonist
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BCC1082
CP-945598 HCl
Otenabant Hydrochloride is a potent and selective cannabinoid receptor CB1 antagonist with Ki of 0.7 nM, exhibits 10,000-fold greater selectivity against human CB2 receptor.