Others Products Targets
- Voltage-gated Sodium (NaV) Channel (30)
- Voltage-gated Potassium (KV) Channel (38)
- Voltage-gated Calcium Channel (CaV) (38)
- TRPV (30)
- NFKB and IKB (30)
- GABAB Receptor (28)
- Lipoxygenase (8)
- Leukotriene and Related Receptor (13)
- Bradykinin Receptor (12)
- Others (20)
- Glucocorticoid Receptor (9)
- Cytokine Receptor (4)
- Cyclooxygenase (24)
- IRAK (1)
- NK2 Receptor (7)
- NK1 Receptor (15)
- NOP Receptor (21)
- Mu-Opioid Receptors (15)
- Kappa Opioid Receptors (14)
- Glutamate (Metabotropic) Group III Receptor (26)
- Glutamate (Metabotropic) Group II Receptor (33)
- Glutamate (Metabotropic) Group I Receptor (54)
- AMPA Receptor (45)
- GABAA-ρ Receptor (8)
- GABAA Receptor (66)
- GPR55 (8)
- CB2 Receptor (6)
- CB1 Receptor (17)
- Nicotinic (α7) Receptor (25)
- Nicotinic (α4β2) Receptor (14)
- NK3 Receptor (5)
- NMDA Receptor (87)
- Kainate Receptor (22)
- CCK2 Receptor (7)
- CCK1 Receptor (3)
- NO donors and precursors (9)
- nNOS (5)
- iNOS (11)
- eNOS (1)
- Delta opioid receptor (16)
- Purinergic (P2X) Receptor (32)
- Prostanoid Receptor (24)
Products for Others - Page 30
- Cat.No. Product Name Information/Activity
-
BCC1578
Flecainide acetate
Flecainide acetate (R-818) is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia; works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac action potential.
-
BCC6270
Huwentoxin IV
526224-73-7
-
BCC6358
ICA 121431
ICA-121431 is a nanomolar potent and broad-spectrum voltage-gated sodium channel (Nav) blocker, shows equipotent selectivity for human Nav1.1 and Nav1.3 subtypes with IC50 values of 13 nM and 23 nM, respectively. ICA-121431 shows less potent inhibition of Nav1.2 (IC50=240 nM) and 1,000 fold selectivity against Nav1.4, Nav1.6, and the TTX-resistant human Nav1.5 and Nav1.8 channels (IC50s >10 µM).
-
BCC6327
Jingzhaotoxin III
925463-91-8
-
BCC7618
KC 12291 hydrochloride
181936-98-1
-
BCC7794
Licarbazepine
29331-92-8
-
BCC4677
Mexiletine HCl
Mexiletine hydrochloride (KOE-1173 hydrochloride), a Class IB antianhythmic, is a non-selective voltage-gated sodium channel blocker.
-
BCC5077
Oxcarbazepine
Oxcarbazepine (GP 47680) inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 μM and also inhibits the influx of 22Na+ into rat brain synaptosomes with IC50 about 100 μM.
-
BCC6328
Phrixotoxin 3
880886-00-0
-
BCC6103
ProTx II
ProTx II is a selective blocker of Nav1.7 sodium channels with an IC50 of 0.3 nM, and is at least 100-fold selective for Nav1.7 over other sodium channel subtypes. ProTx-II inhibits sodium channels by decreasing channel conductance and shifting activation to more positive potentials and blocks action potential propagation in nociceptors.
