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Cat.No. Product Name Information/Activity

BCC7806 JNJ 303 JNJ 303 is a potent IKs blocker with an IC50 value of 64 nM. JNJ 303 does not have any effects on other cardiac channels at concentrations of 3.3 μM for INa, Ica, Ito, and IKr. JNJ 303 induces QT-prolongations and causes unprovoked torsades de pointes (TdP). JNJ 303 chemical structure

BCC7710 Kaliotoxin 145199-73-1 Kaliotoxin chemical structure

BCC1682 KN-92 phosphate KN-92 phosphate is an inactive derivative of KN-93. KN-92 phosphate chemical structure

BCC1683 KN-93 CaM kinase II inhibitor; also K+ channel blocker (KV),KN-93 is a novel membrane-permeant synthetic inhibitor of purified neuronal CaMK-II, with Ki of 370 nM. KN-93 chemical structure

BCC7231 Linopirdine dihydrochloride 113168-57-3 Linopirdine dihydrochloride chemical structure

BCC7709 Margatoxin Margatoxin, an alpha-KTx scorpion toxin, is a high affinity inhibitor of Kv1.3 (Kd=11.7 pM). Margatoxin inhibits the Kv1.2 (Kd=6.4 pM) and Kv1.1 (Kd=4.2 nM). Margatoxin, a 39 amino-acid-long peptide, is isolated from the venom of the scorpion Centruroides margaritatus and widely used in ion channel research. Margatoxin chemical structure

BCC7927 Psora 4 Potent KV1.3 channel blocker Psora 4 chemical structure

BCC6044 RuBi-4AP 851956-02-0 RuBi-4AP chemical structure

BCC5990 ShK-Dap22 220384-25-8 ShK-Dap22 chemical structure

BCC3866 Terfenadine Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9. Terfenadine chemical structure

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