Allergy Research
Allergy is a hypersensitivity disorder characterized by an exaggerated immunologic response to an otherwise innocuous agent, called an allergen. Allergies can be caused by both host (race, gender, hereditary) and environmental factors (pollution, diet, infection).
Allergy Research Products Targets
Products for Allergy Research - Page 4
- Cat.No. Product Name Information/Activity
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BCC4542
Fexofenadine HCl
Fexofenadine hydrochloride (MDL-16455 hydrochloride), a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial (person aged ≥16 years).
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BCC1262
Loratadine
Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity.
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BCC6740
Mepyramine maleate
Mepyramine maleate, a first generation antihistamine, is an antagonist of histamine H1 receptor, with Kds of 0.8 nM, 5200 nM and >3000 nM for H1, H2, and H3 receptor, respectively, and a pKd of 9.4 for H1 receptor.
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BCC4923
Mirtazapine
Mirtazapine is a 5-HT receptor inhibitor. Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent by blocking 5-HT2 and 5-HT3 receptors.
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BCC4545
Olopatadine HCl
Olopatadine hydrochloride (ALO4943A) is a histamine blocker used to treat allergic conjunctivitis.
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BCC3866
Terfenadine
Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.
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BCC6742
trans-Triprolidine hydrochloride
550-70-9
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BCC7838
Zotepine
26615-21-4
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BCC7576
BAY-u 9773
Dual CysLT<sub>1</sub> and CysLT<sub>2</sub> antagonist
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BCC7244
Cinalukast
128312-51-6
