GPR35 - GPCR/G protein

Cat.No. Product Name Information

BCC7876 ML 145 ML 145 is a selective GPR35/CXCR8 antagonist with an IC50/EC50 of 20.1 nM, but not for the related GPR55 orphan receptor. GPR35 is expressed by various cells of the immune system and it may has potential as a therapeutic target in inflammatory disease. ML 145

BCC7906 Methyl 5-{2-[(tert-butylamino)carbothioyl]carbohydrazonoyl}-1-(2,4-difluorophenyl)-1H-pyrazole-4-carboxylate GPR35 antagonist

BCC6859 Zaprinast Zaprinast (M&B 22948) is an inhibitor of cGMP-selective Phosphodiesterases(PDEs). Zaprinast is a G protein-coupled receptor (GPR) 35 agonist which activates rat GPR35 strongly and activates human GPR35 moderately. Zaprinast reduces vessel remodeling through antiproliferative and proapoptotic effects.

BCC6188 YE 120 YE 120

BCC6316 TC-G 1001

BCC7909 Pamoic acid disodium salt

BCC8036 TCS 3035 GPR35 agonist

Products for GPR35