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Melanin-concentrating Hormone Receptors

Two Melanin-concentrating hormone receptors (MCHR) have recently been characterized: MCH-R1 and MCH-R2. These two receptors share approximately 38% homology.Antagonists might be useful in the treatment of obesity and anxiety and depression. An agonist might have possible utility as a treatment for osteoporosis and insomnia.Research is ongoing for antagonists affecting MCH receptors R1 and R2.

Products for Melanin-concentrating Hormone Receptors

Cat.No. Product Name Information
BCC6024 [Ala17]-MCHPotent MCH receptor agonist
BCC6068 MCH (human, mouse, rat)Potent endogenous MCH agonist
BCC6149 TC-MCH 7cSelective melanin-concentrating hormone receptor 1 (MCH₁R) antagonist
BCC7657 ATC 0175 hydrochlorideMCH₁ antagonist; also 5-HT_2B antagonist and 5-HT_1A partial agonist
BCC7658 SNAP 94847 hydrochloridePotent and selective MCH₁ antagonist
BCC7666 ATC 0065Potent and selective MCH₁ antagonist
BCC7897 GW 803430MCH₁ antagonist