Products for Melanin-concentrating Hormone Receptors
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BCC6068
MCH (human, mouse, rat)
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BCC6024
[Ala17]-MCH
![[Ala17]-MCH](/media/images/struct/BCC6024.png)
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BCC7658
SNAP 94847 hydrochloride
SNAP 94847 is a novel, high affinity selective melanin-concentrating hormonereceptor1 (MCHR1) antagonist with (Ki= 2.2 nM, Kd=530 pM), it displays >80-fold and >500-fold selectivity over MCHα1A and MCHD2 receptors respectively. SNAP 94847 binds with high affinity to the mouse and rat MCHR1 with minimal cross-reactivity to other GPCR, ion channels, enzymes, and transporters.
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BCC7666
ATC 0065
Potent and selective MCH<sub>1</sub> antagonist
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BCC7657
ATC 0175 hydrochloride
MCH<sub>1</sub> antagonist; also 5-HT<sub>2B</sub> antagonist and 5-HT<sub>1A</sub> partial agonist
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BCC7897
GW 803430
GW-803430 (GW-3430) is a potent and selective melanin-concentrating hormone receptor 1 (MCH R1) antagonist with a pIC50 of 9.3. GW-803430 is orally active in an animal model of obesity.
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BCC6149
TC-MCH 7c
TC-MCH 7c, a phenylpyridone derivative, is an orally available, selective and brain-penetrable MCH1R antagonist with an IC50 of 5.6 nM for hMCH1R. TC-MCH 7c has Kis of 3.4 nM and 3.0 nM of human and mouse MCH1R, respectively.
