Vasopressin Receptor - GPCR/G protein

Cat.No. Product Name Information

BCC7812 OPC 21268 Fuscoside (OPC-21268) is an orally effective, nonpeptide, vasopressin V1 receptor antagonist with an IC50 of 0.4 μM.

BCC5095 Mozavaptan Mozavaptan (OPC-31260) is a benzazepine derivative and a potent, selective, competitive and orally active vasopressin V2 receptor antagonist with an IC50 of 14 nM. Mozavaptan shows ~85-fold selectivity for V2 receptor over V1 receptor (IC50 of 1.2 μM), and can antagonize the antidiuretic action of arginine vasopressin (AVP) in vivo. Mozavaptan has the potential for hyponatremia, syndrome of inappropriate antidiuretic hormone (SIADH), and congestive heart failure treatment.

BCC7324 SR 49059

BCC5096 Tolvaptan Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28μM for the inhibition of AVP-induced platelet aggregation.

BCC1525 Desmopressin Synthetic vasopressin analog; V<sub>1B</sub> and V<sub>2</sub> agonist,Desmopressin(DDAVP) is the synthetic analogue of the antidiuretic hormone arginine vasopressin.

BCC3756 Conivaptan HCl Conivaptan (hydrochloride) is a non-peptide antagonist of vasopressin receptor, with Ki values of 0.48 and 3.04 nM for rat liver V1A receptor and rat kidney V2 receptor respectively.

BCC5981 d[Leu4,Lys8]-VP

BCC1526 Desmopressin Acetate Desmopressin(DDAVP) acetate is the synthetic analogue of the antidiuretic hormone arginine vasopressin.

BCC6011 (d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin

BCC5314 Atosiban Atosiban(RW22164; Tractocile) is a nonapeptide, desamino-oxytocin analogue, and a competitive vasopressin/oxytocin receptor antagonist (VOTra).

Products for Vasopressin Receptor