BCC3913
ETP-46464
ETP-46464 is a potent and selective inhibitor of ATR with IC50 of 25 nM.
BCC3933
NU 7026
NU 7026 (LY293646) is a novel specific DNA-PK inhibitor with IC50 of 0.23 μM, also inhibits PI3K with IC50 of 13 μM.
BCC1518
Daun02
Daun02 is a prodrug of the topoisomerase inhibitor Daunorubicin.
BCC3679
NU7441 (KU-57788)
KU-57788 is a potent and selective inhibitor of DNA-PK with an IC50 of 13 nM, with selectivity over a range of kinases including mTOR, PI 3-K, ATM and ATR.
BCC1110
KU-0060648
KU-0060648 is a dual inhibitor of PI3K and DNA-PK with IC50s of 4 nM, 0.5 nM, 0.1 nM, 0.594 nM and 8.6 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ and DNA-PK, respectively.
