Products for Smoothened
- Cat.No. Product Name Information
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BCC5154
PF-04449913
Glasdegib (PF-04449913) is a potent and orally bioavailable smoothened inhibitor. Glasdegib (PF-04449913) binds to human SMO (amino acids 181-787) with an IC50 of 4 nM.
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BCC6254
SMANT hydrochloride
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BCC1693
LDE225 Diphosphate
Erismodegib diphosphate (Sonidegib diphosphate) is a potent and selective Smo antagonist with IC50 of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively.
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BCC6329
GSA 10
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BCC7950
MRT 10
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BCC3641
Purmorphamine
Purmorphamine (Shh Signaling Antagonist VI) is a smoothened receptor agonist with an EC50 of 1 μM.
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BCC1617
HhAntag
HhAntag is a small molecule inhibitor of GLI1-mediated transcription, an essential down-stream element of the Hedgehog (Hh) pathway; antitumor agent.
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BCC5066
LDE225 (NVP-LDE225,Erismodegib)
Erismodegib (Sonidegib) is a potent and selective Smoothened (Smo) antagonist with IC50s of 1.3 nM and 2.5 nM for mouse and human Smo, respectively.
