Products with Activators Bioactivity

Explore BioCrick products associated with Activators biological activity, including catalog numbers, product names and available bioactivity information.

Cat. No.	Product Name
BCN4430	Methyl syringate
Methyl syringate is a specific and selective activator of hTRPA1, can regulate food intake and gastric emptying through a TRPA1-mediated pathway and, by extension, can contribute to weight suppression. Methyl syringate has a unique inhibitory activity toward aflatoxin production. Methyl syringate could be effective to suppress hypoxia-induced inflammation, it inhibits the hypoxic induction of COX-2 expression and cell invasion through TRPA1 activation.
BCN4701	Bisandrographolide A
1. Bisandrographolide A activates TRPV4 channels, could play a role in some of the effects of Andrographis extract described in traditional medicine.
BCN4743	Eriodictyol-7-O-glucoside
1. Eriodictyol-7-O-glucoside and epicatechin appears to be responsible for the antioxidant activity of pistachio skin. 2. Eriodictyol-7-O-glucoside has protective effect on cisplatin-induced toxicity was investigated in a human renal mesangial cell line, HRMC. 3. Eriodictyol-7-O-glucoside can activate Nrf2/ARE signaling, directly associated with its neuroprotection against oxidative stress-induced ischemic; suggests that targeting the Nrf2/ARE pathway may be a promising approach for therapeutic intervention in stroke.
BCN4749	Nelumol A
1. Nelumol A, and nelumal A show a potency comparable to the endogenous ligand, they may as a valuable potential novel lead compound in the search for FXR agonists.
BCN4843	Pterisolic acid B
1. Pterisolic acid B (J19) is an effective Nrf2 activator. we have also identified a more potent natural product analogue J19-1, J19-1 shows significant cytoprotective effect against cisplatin-induced cytotoxicity in HKC cells.

Activators Bioactivity Products