Products with Anti-apoptotic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2508 | Schisanhenol |
| Schisanhenol has antioxidative effect on human LDL oxidation, may be through scavenging free radicals; it also has anti-apoptosis effect on BACSs, may be related to its inhibition of ROS generation. Schisanhenol can protect against adriamycin induced heart mitochondrial toxicity. | |
| BCN2554 | 20R-Ginsenoside Rg2 |
| Ginsenoside Rg2 may have a therapeutic potential for type 2 diabetic patients, it suppresses the hepatic glucose production via AMPK-induced phosphorylation of GSK3βand induction of SHP gene expression .Ginsenoside Rg2 can protect H9c2 cells against H2O2- induced injury through its actions of anti-oxidant and anti-apoptosis.20R-Ginsenoside Rg2 inhibits the cytokine interleukin 1 alpha (IL-1α)-induced reduction in gap junction-mediated intercellular communication (GJIC). | |
| BCN2852 | Picfeltarraenin IV |
| Picfeltarraenin IV is a natural product from Picria felterrae Lour. | |
| BCN3328 | Notoginsenoside R2 |
| 1. Notoginsenoside R2 has neuroprotection against 6-OHDA-induced neurotoxicity, is associated with Notoginsenoside R2-mediated P90RSK and Nrf2 activation through MEK1/2-ERK1/2 pathways. | |
| BCN4090 | Uridine |
| Uridine has antidepressant-like effects, and it has protective effects against drug-induced fatty liver. Uridine can increase the rate of potassium transport in mitochondria isolated from liver of low resistant rats, and inhibitors of the channel prevent the channel activating effect of Uridine. Uridine has inhibition of p53-dependent intestinal apoptosis initiated by 5-fluorouracil. | |
