Products with Anti-filaria bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1862 | Tirandamycin B |
| 1. Tirandamycin B is a BmAsnRS inhibitor. 2. Tirandamycin B is a leading anti-filarial drug . 3. Tirandamycin B has antitumor and antibacterial activities. | |
| BCN5466 | Hirsutanonol |
| 1. Hirsutanonol or oregonin as an active ingredient composition for treating atopic dermatitis. 2. Hirsutanonol shows significant inhibitory effects on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced cyclooxygenase-2 (COX-2) expression in immortalized human breast epithelial MCF10A cells. 3. Hirsutanonol has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid peroxidation. 4. Hirsutanonol shows potent cytotoxic activities against murine B16 melanoma cells and human SNU-C1 gastric cancer cells. 5. Hirsutanonol has chemoprotective effect on human lymphocytes DNA. 6. Hirustenone and hirsutanonol show promising anti-filarial activity both in vitro and in vivo studies. | |
| BCN5467 | Hirsutenone |
| 1. Hirsutenone exhibits anti-cancer effect against prostate cancer through a direct physical inhibition of Akt1/2. 2. Hirsutenone attenuates adipogenesis by directly targeting PI3K and ERK during MCE in 3T3-L1 preadipocytes, underscoring the potential therapeutic application of Hirsutenone in preventing obesity. 3. Hirsutenone may exert a preventive effect against microbial endotoxin lipopolysaccharide-induced inflammatory skin diseases through inhibition of ERK pathway-mediated NF-kappaB activation. 4. Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid peroxidation. 5. Hirsutenone shows potent cytotoxic activities against murine B16 melanoma cells and human SNU-C1 gastric cancer cells. 6. Hirustenone and hirsutanonol show promising anti-filarial activity both in vitro and in vivo studies. | |
