Products with Anti-hyperlipidemic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2912 | Hydroxycitric acid |
| 1. (-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of action of HCA appears to be related to its ability to act as a competitive inhibitor of the enzyme ATP-citrate lyase, which catalyzes the conversion of citrate and coenzyme A to oxaloacetate and acetyl coenzyme A (acetyl-CoA), primary building blocks of fatty acid and cholesterol synthesis. 2. Hydroxycitric acid ameliorates high-fructose-induced redox imbalance and activation of stress sensitive kinases in male Wistar rats through its hypolipidemic effects. | |
| BCN2967 | Quercetin Dihydrate |
| Quercetin dihydrate loaded electrospun nanofibrous membrane show antimycotic effect on candida albicans. Clinoptilolite modified with quercetin dihydrate has shown better cytotoxicity compared with clinoptilolite modified with quercetin. The supplementation of quercetin dihydrate and gallate promotes an increase in fecal sterols, which in turn leads to a decreased absorption of dietary cholesterol as well as lower plasma and hepatic cholesterol. | |
| BCN3181 | Campesterol |
| Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects, it and other plant sterols often decrease LDL cholesterol levels overall. Campesterol has anti-inflammatory effect, it inhibits several pro-inflammatory and matrix degradation mediators typically involved in osteoarthritis- induced cartilage degradation, also sometimes used to treat some specific prostate conditions. | |
| BCN3476 | Isosalvianolic acid C |
| 1. Isosalvianolic acid C exhibits more potent activity than probucol except for salvianolic acid F . | |
| BCN3515 | Rhapontigenin |
| Rhapontigenin has antioxidative, antihyperlipidemic, antifungal and anticancer activities. Rhapontigenin inhibits HIF-1α accumulation and angiogenesis in PC-3 prostate cancer cells, suppresses breast cancer cell migration and invasion, which is involved in inhibiting the PI3K-dependent Rac1 signaling pathway. Rhapontigenin exhibits dose-dependent inhibition of tyrosinase activity and melanin synthesis in B16F10 melanoma cells. | |
