Products with Anti-inflammatory bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2696 | Pogostone |
| Pogostone possesses potent anti-bacterial and anti-fungal activities, it also exhibits an immunosuppressive property by directly blocking T cell proliferation as well as altering inflammatory cytokine profile. Pogostone could exert a gastro-protective effect against gastric ulceration, and the underlying mechanism might be associated with the stimulation of PGE2, improvement of antioxidant and anti-inflammatory status, as well as preservation of NP-SH. | |
| BCN2705 | (20S)-Protopanaxatriol |
| (20S)-Protopanaxatriol is a metabolite of ginsenoside, works through the glucocorticoid receptor (GR) and oestrogen receptor (ER), and is also a LXRα inhibitor. (20S)-Protopanaxatriol shows strong and selective antimicrobial activity, it also has anti-oxidant activity. (20S)-Protopanaxatriol exerts cardioprotective effects against myocardial ischemic injury, by enhancing the anti-free-radical actions of heart tissues. | |
| BCN2709 | Isorhamnetin 3-glucuronide |
| 1. Isorhamnetin - 3 -O -glucuronide exerts anti-inflammatory activity by increasing heme oxygenase-1 (HO-1) expression and by suppressing Jun N-terminal kinase (JNK) and p38 signaling pathways in LPS-challenged RAW264.7 macrophage cells. 2. Isorhamnetin-3-glucuronide(1 mg/kg i.v.) can progressively reduce mean blood pressure (MBP), measured in conscious spontaneously hypertensive rats (SHR). 3. Isorhamnetin 3-glucuronide can inhibit vascular cell adhesion molecule-1 (VCAM-1) cell surface expression at 2 micromol/L, indicates that it can inhibit the expression of key molecules involved in monocyte recruitment during the early stages of atherosclerosis at physiological concentrations. | |
| BCN2712 | Chiisanoside |
| 1. Chiisanoside has anti-rotaviral activity. 2. Chiisanoside inhibits NO and PGE2 production. 3. Chiisanoside has the potential to prevent obesity as a lipase inhibitor which suppresses fat absorption in vivo. 4. Chiisanoside has anti-oxidant activity, can inhibit xanthine oxidase activity and increase superoxide dismutase (SOD), glutathione peroxidase and catalase . 5. Chiisanoside has anti-inflammatory property, might be the result from the inhibition of iNOS, COX-2, TNF-alpha and IL-1beta expression through the down-regulation of NF-kappaB binding activity. | |
| BCN2722 | Columbamine |
| Columbamine exerts anti-proliferative and anti-vasculogenic effects on metastatic human osteosarcoma U2OS cells with low toxicity. It shows strong acetylcholinesterase (AChE) inhibitory activity with IC50 48.1 µM. | |
