Products with Anti-inflammatory Bioactivity

Explore BioCrick products associated with Anti-inflammatory biological activity, including catalog numbers, product names and available bioactivity information.

Cat. No.	Product Name
BCN2271	Gomisin N
Gomisin N has anti-oxdiant, anti-inflammatory, anti-cancer and anti-hepatitis activities; it produces beneficial sedative and hypnotic bioactivity, which may be mediated by the modification of the serotonergic and GABAergic system. Gomisin N can enhance TNF-α-induced apoptosis by suppressing of NF-κB and EGFR signaling pathways, and potentiate TRAIL-induced apoptosis through ROS-mediated up-regulation of death receptors 4 and 5.
BCN2280	Saponarin
1. Saponarin, which isolated from Gypsophila trichotoma Wend, shows in vitro and in vivo hepatoprotective and antioxidant activity against CCl4-induced liver damage. 2. Saponarin has antioxidant activity against cocaine-induced oxidative stress and hepatotoxicity. 3. Saponarin exerts anti-inflammatory effects in LPS-induced RAW 264.7 macrophages via inhibition of NF-κB, ERK and p38 signaling. 4. Saponarin shows hypoglycemic activity in the range of 20-80 mg/kg compared to 100-200 mg/kg for acarbose as reported. 5. Saponarin is characterized as α-glucosidase inhibitor present in Tinospora cordifolia, it also has hypoglycemic activity. 6. Saponarin exerts slight antihypertensive activity in non-diabetic spontaneously hypertensive rats (SHR), however, such effect is not observed in streptozotocin-induced diabetic SHR (SHR-D), indicates that diabetes and hypertension in combination are more difficult to be modulated by saponarin.
BCN2291	Diacerein
Diacerein, a interleukin-1 beta inhibitor, is a slow-acting medicine of the class anthraquinone used to treat joint diseases.The feasibility of targeted delivery of Diacerein to articular tissue using soluble polysaccharide chondroitin sulfate as the targeting vector, this approach has the potential to significantly increase anti-arthritic drug concentration in joints without leading to systemic toxicity.
BCN2294	Sophoricoside
Sophoricoside has anti-inflammatory, anti-cancer, anti-bone loss, and immunosuppressive effects. Sophoricoside is an effective regulator of lipogenesis and glucose consumption and may find utility in the treatment of obesity and type 2 diabetes. Sophoricoside exposure reduced the number of implanted embryos in a dose-dependent manner and failed the embryo implantation through altering the morphology of uterine and compromising the endometrial receptivity.
BCN2295	Desmethoxy yangonin
Desmethoxyyangonin is a reversible inhibitor of MAO-B, it may have important therapeutic value for treatment of neurodegenerative disorders and Parkinson's Disease. Desmethoxy yangonin protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways.

Anti-inflammatory Bioactivity Products