Products with
Anti-inflammatory bioactivity
Cat.No.
|
Product Name
|
BCN1682 |
Ginkgolide B
|
Ginkgolide B has potent neuroprotective, anti-arrhythmias, anti-inflammatory and anti-apoptotic effects, it might be a promising drug on inhibiting platelet function and reducing inflammation in atherosclerosis.Ginkgolide B retards the proliferation and development of mouse embryonic stem cells (ESCs) and blastocysts in vitro and causes developmental injury in vivo. |
BCN1710 |
3',5,5',7-Tetrahydroxyflavanone
|
1. 5,7,3',5'-Tetrahydroxyflavanone has inhibitory effects on HIV-1 reverse transcriptase (RT)-associated RNase H function, it may have antiviral activity against HIV-1.
2. 5,7,3',5'-Tetrahydroxyflavanone has anti-inflammatory properties, it can inhibit nitric oxide (NO) production with IC50 values of 18.5 uM, the inhibitory effect is accompanied by dose-dependent decreases in LPS-induced nitric oxide synthase (iNOS) in RAW 264.7 cells. |
BCN1715 |
beta-Amyrin acetate
|
1. beta-Amyrin acetate and β-amyrin palmitate as antidyslipidemic agents, they show significant HMG-CoA-reductase inhibition.
2. beta-Amyrin acetate and honokiol exhibit sEH inhibitory activity.
3. beta-Amyrin acetate has a high antioxidant potential with an IC50 value of 158.2ug/mL, and has cytotoxicity , it could be a viable source of antioxidant and cytotoxic agents in cancer chemotherapy in the near future.
4. beta-Amyrin acetate has anti-inflammatory activity,with ID50 values in the range of 0.15-0.75 micromol/ear.
5. beta-Amyrin acetate exhibits weak-moderate antiproliferative activity against the A2780 human ovarian cancer cell line. |
BCN1904 |
Convolvine
|
1. Convolvine and its derivatives exhibit pronounced antihypoxic, immunomodulating, and anti-inflammatory activity.
2. Convolvine blocks the M-receptors of the heart and intestine but raises the sensitivity of the M-receptors of the salivary gland and of the CNS,convolvine has revealed characteristics of a sedative and nootropic agent.
3. Convolvine and its derivatives exhibit cytotoxic activity, the alkaloids N-benzylconvolvine and N-chloroacetylconvolvine at concentrations of 10 ug/mL exhibit the greatest activity against HeLa and Hep cancer cell cultures. |