Products with Anti-inflammatory bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1083 | Eleutheroside E |
| Eleutheroside E(EE) has anti-inflammatory and protective effects in ischemia heart, the beneficial effect of EE may provide an effective and powerful strategy to alleviate behavioral alterations induced by sleep deprivation, it may influence to immune-enhancing through increasing the physical endurance capacity and immune cell activation. EE significantly decreases the inflammatory cell infiltration, pannus formation, cartilage damage, bone erosion of CIA mice, the generation of TNF-α and IL-6, the metabolism of drugs metabolized via CYP2C9 and CYP2E1. | |
| BCN1086 | Saikosaponin A |
| Saikosaponin A has a variety of pharmacological benefits, including antiepileptic, anti-osteoporosis, antioxidant, anti-inflammatory, immunomodulatory, and anti-bacterial activities. It extends to alcohol self-administration the capacity to suppress morphine and cocaine self-administration in rats, and can effectively attenuate neuropathic pain in CCI rats by inhibiting the activation of p38 MAPK and NF-κB signaling pathways in spinal cord. It can inhibit NMDA receptor current and persistent sodium current, and inhibit the TNF-α level, the IL-1β production, and cysteine-aspartic acid protease (caspase)-1 activity. | |
| BCN1090 | Arctiin |
| Arctiin(NSC 315527), a plant lignan that can be extracted from the Arctium lappa (burdock) seeds, is a possible environmental endocrine disruptor compounds and have been shown to influence sex hormone metabolism as well as protein synthesis, steroid biosynthesis. Arctiin has been reported to have preventing obesity, antibacterial, antiviral, anti-inflammatory, and anti-oxidant effects in vitro. Arctiin inhibits adipogenesis in 3T3-L1 adipocytes through the inhibition of PPARγ and C/EBPα and the activation of AMPK signaling pathways. Arctiin also has a protective effect on ROS-induced cell dysfunction in HHDPCs and may therefore be useful for alopecia prevention and treatment strategies. | |
| BCN1094 | Peimine |
| Peimine has good anti-inflammatory effects in vivo, it inhibits the production of inflammatory cytokines induced by LPS through blocking MAPKs and NF-κB signaling pathways. It also has antitussive and sedative actions, the action being suspected to be central in nature. | |
| BCN1095 | Peiminine |
| Peiminine has potent anti-inflammatory, anti-allergic, antitussive, and expectorant effects. It induces autophagic cell death thus represses colorectal carcinoma tumor growth. Peiminine can inhibit lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury, by reducing circulating IFN-γ levels and inhibiting signal transduction pathways involving TGF-β, CTGF, ERK1/2, NF-κB and FasL. | |
