Products with Anti-insulin bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1206 | Palmitic acid |
| Palmitic acid induces anxiety-like behavior in mice while increasing amygdala-based serotonin metabolism, it induces down-regulation of APOM expression, is mediated via the PPARβ/δ pathway. Palmitic acid induces degeneration of myofibrils and modulate apoptosis in rat adult cardiomyocytes. it also shows in vivo antitumor activity in mice. Palmitic acid is CNS mediated via PKC-theta activation, resulting in reduced insulin activity. | |
| BCN1808 | Lavendustin A |
| 1. Lavendustin A and hormothamnione exhibit cytotoxic effects on tumor cell lines. 2. Lavendustin A is a potent tyrosine kinase inhibitor of the epidermal growth factor (EGF) receptor, and an angiogenesis inhibitor. 3. Lavendustin A is a hyperbolic mixed-type inhibitor with respect to both ATP and the peptide substrate, with a major effect on the binding affinities for both substrates. 4. Lavendustin A at 0.1 nM-1 microM causes a concave-shaped inhibition of the insulin release stimulated by 7 mM glucose, the inhibitory effect can be overcomed by higher concentrations of glucose. | |
| BCN4095 | Sissotrin |
| 1. Sissotrin can impair glucose tolerance. | |
