Products with Antiarrhythmic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2974 | Dehydroevodiamine |
| Dehydroevodiamine has anticholinesterase activity and an anti-amnesic effect, it also may be a novel and effective ligand for improvement of beta-amyloid type amnesia. Dehydroevodiamine has antiarrhythmic, and anti-inflammatory properties, the effect of dehydroevodiamine-mediated inhibition of the expression LPS-induced iNOS and COX-2 genes is due to under the suppression of NF-kappaB activation in the transcriptional level. | |
| BCN3296 | Dicentrine |
| 1. Dicentrine has antinociception in different models of chemical pain. 2. Dicentrine induces DNA lesions to arrest cell cycle. 3. Dicentrine, a selective α(1)-adrenoceptor antagonist with potent antiarrhythmic and antihypertensive activities. 4. Callus and cell suspension cultures of S. venosa can produce high levels of Dicentrine as an alternative source of plant materials. | |
| BCN3412 | Astringin |
| 1. Astringinin is a potent antiarrhythmic agent with cardioprotective activity in ischemic and ischemic-reperfused rat heart, the beneficial effects of astringinin in the ischemic and ischemic-reperfused hearts may be correlated with its antioxidant activity and upregulation of NO production. 2. Astringinin can significantly attenuate proinflammatory responses and hepatic injury after trauma-hemorrhage, the salutary effects of astringinin administration on attenuation of hepatic injury following trauma-hemorrhage are likely due to reduction of pro-inflammatory mediator levels. | |
| BCN3867 | Ajmaline |
| 1. Ajmaline is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or ventricular tachycardia. 2. Ajmaline inhibits cardiac Kv1.5 and Kv4.3 channels at therapeutic concentrations. | |
| BCN4126 | Phlorizin |
| Phlorizin is a non-selective SGLT inhibitor with Kis of 300 and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor. Phlorizin may be a novel therapeutic approach for the treatment of diabetic nephrolog, it protects mice from diabetic nephrology. Phlorizin prevents ventricular tachyarrhythmia through the improvement of impulse conduction slowing during ischemia. | |
