Products with Antibacterial bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4184 | Taraxasterol acetate |
| Taraxasterol acetate has anti-inflammatory activity in bino rats against carrageenan, formaldehyde and adjuvant induced inflammations in doses between 10 and 100 mg/kg. Taraxasterol acetate also displays potential antibacterial activities. | |
| BCN4206 | Cirsimaritin |
| 1. Cirsimaritin has antibacterial, anti- inflammation, anti-tumor, antioxidant, renal protection and so on. 2. Cirsimaritin has potential use in patients with congestive heart failure, it can mitigate cardiac remodeling and left ventricular dysfunction through augmenting myocardial autophagy and decreasing matrix metalloproteinase-2&9 activities. 3. Cirsimaritin inhibits the growth of tumor cells and induced mitochondrial apoptosis in human gallbladder carcinoma cell line (GBC-SD), it triggers endoplasmic reticulum (ER) stress and down-regulates the phosphorylation of Akt. 4. Cirsimaritin increases tyrosinase activity and melanin content in murine B16F10 melanoma cells by activation of CREB as well as upregulation of MITF and tyrosinase expression in a dose-dependent manner;support the putative application of cirsimaritin in ultraviolet photoprotection and hair coloration treatments. 5. Cirsimaritin shows moderate anti-proliferative activity against COLO-205 cells with IC 50 values of 13.1uM. | |
| BCN4222 | Moronic acid |
| 1. Moronic acid shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity. 2. Moronic acid is a new structural lead for anti-EBV drug development, can substantially reduce the numbers of EBV particles produced by the cells after lytic induction. 3. Moronic acids inhibits the capacity of Rta to activate a promoter that contains an Rta-response element, indicating that Moronic acid interferes with the function of Rta. 4. Moronic acid shows significant anti-HIV activity (EC(50) 186) and was modified to develop more potent anti-AIDS agents. 5.Morolic and moronic acids have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediated by inhibition of 11β-HSD 1 as indicated by in vitro. | |
| BCN4224 | Cabraleadiol |
| 1. Cabraleadiol inhibits photosystem II (PS II) and induces the appearance of small G band which is related with the decreased plastoquinone (PQ) pool reduction. 2. Cabraleadiol displays antimycobacterial activity against Mycobacterium tuberculosis, it also is weakly cytotoxic to a breast cancer (BC) cell line. | |
| BCN4233 | Rediocide C |
| 1. Rediocide C exhibits potent activity against D. pteronyssinus with respective LC50 values of 5.59 microg/cm2. 2. Rediocide C and rediocide G exhibit antimycobacterial activity, with the MIC value of 3.84 uM. | |
