Products with Antibacterial bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4618 | Isopimaric acid |
| 1. Isopimaric acid is active against MDR and MRSA strains of S. aureus which are becoming increasingly resistant to antibiotics, the minimum inhibitory concentrations (MIC) are 32-64 microg/mL . 2. Isopimaric acid is also possible that an antagonistic interaction with reserpine may render the antibiotics inactive. | |
| BCN4627 | Totarol |
| 1. Totarol has anti-bacteria effect by restraining bacterial growth by perturbing the cell division and proliferation, including several pathogenic Gram-positive bacteria, mycobacterium tuberculosis. 2. Totarol treatment leads to metabolic shutdown by repressing the major central metabolic dehydrogenases in B. subtilis. | |
| BCN4677 | Epitaraxerol |
| 1. Epitaraxerol shows moderate antifungal activity against C. albicans and low antimicrobial activity against T. mentagrophytes, A. niger, S. aureus, E. coli, P. aeruginosa, and B. subtilis. | |
| BCN4690 | Goniothalamin |
| 1. Goniothalamin enhances rather than inhibits the ATPase activity of a cyanobacterial Hsp90 (HtpG) and a yeast Hsp90, increases both K(m) and k(cat) of the Hsp90s. 2. Goniothalamin induces oxidative stresses and inhibits the expression of cell wall-associated proteins resulting in growth inhibition of Arabidopsis seedlings. 3. Goniothalamin has gastroprotective activity which is inhibited after pre-treatment with NEM (N-ethylmaleimide) and NSAID (non-steroidal anti-inflammatory drugs), highlighting the importance of sulfhydryl compounds and prostaglandins on Goniothalamin activity. 4. Goniothalamin is a natural product that has been demonstrated to induce apoptosis in various cancer cell lines, can induce cytotoxicity and apoptosis on RT4 cells, induce apoptosis on HepG2 liver cancer cells via induction of caspase-3 with less sensitivity on the cell line of Chang cells. | |
| BCN4695 | Evofolin C |
| 1. Evofolin C and its acetate show strong antifungal and antibacterial activity. 2. Evofolin C exhibits potent inhibition against N-formylmethionylleucylphenylalanine-induced superoxide production with IC(50) values less than 12 microM. | |
