Products with Antibacterial bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4252 | Eburicol |
| 1. Eburicol inhibit the large accumulation of C-14 methyl sterols and cell lysis when the content of ergosterol becomes too low in the actively growing cells. 2. Mutations in the Eburicol gene impact on the activity of the Eburicol protein. | |
| BCN4254 | Moracin C |
| 1. Moracin C and D, new phytoalexins from diseased mulberry, are antifungal compounds. 2. Moracin C has potent antibacterial activity, it can inhibit FabI and fatty acid synthesis, it inhibit S. aureus FabI with IC(50) of 83.8 uM. 3. Moracin C has anti-inflammatory effect, it can effectively reduce lipopolysaccharide (LPS) stimulated up-regulation of mRNA and protein expression of iNOS, COX-2, and serval pro-inflammatory cytokines (IL-1β, IL-6 and TNF-α. 4. Moracin may be protective influence in tumor promotion, utilization of Moracin may open a new avenue in the treatment of tumerigenesis. | |
| BCN4275 | Sarmentosin |
|
1. Sarmentosin significantly lowers the SGPT level of patients suffering from chronic viral hepatitis, and shows a suppressive effect on cell-mediated immune responses in mice. 2. Sarmentosin shows a good effect in lowering serum glutamate-pyruvate transaminase. |
|
| BCN4309 | Artocarpin |
| 1. Artocarpin induces apoptosis in HSC-1 and T47D cells through modulation of MAPK and Akt/mTOR pathways, an extrinsic pathway , respectively . 2. Artocarpin has anti- bactericidal effect, can reduce the viability of pneumococci by a factor of >1000, without obvious harm to lung epithelial cells. 3. Artocarpin can prevent skin damage from UVB irradiation-induced photodamage in hairless mice and this is likely mediated through its antioxidant and anti-inflammation mechanisms. 4. Artocarpin possesses potent 5alpha reductase inhibitory effect. 5. Artocarpin has an efficient lightening effect on UV-stimulated hyperpigmented dorsal skins of brownish guinea pigs. | |
| BCN4322 | Garcinone C |
| 1. Garcinone C is the most potent inhibitor of AChE. 2. Garcinone C is the most active compound against both of pathogenic (MIC =100 μg/ml) and non-pathogenic leptospira (MIC = 200 μg/ml). 3. Garcinone C exhibits either significant or moderate cytotoxicity against MCF-7, A549, Hep-G2 and CNEhuman cancer cell lines in vitro. | |
