Evofolin C

CAS# 163634-05-7

Evofolin C

Catalog No. BCN4695----Order now to get a substantial discount!

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Quality Control of Evofolin C

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Chemical structure

Evofolin C

3D structure

Chemical Properties of Evofolin C

Cas No. 163634-05-7 SDF Download SDF
PubChem ID 44445795 Appearance Powder
Formula C14H18O2 M.Wt 218.29
Type of Compound Phenylpropanoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (E)-3-[4-(3-methylbut-2-enoxy)phenyl]prop-2-en-1-ol
SMILES CC(=CCOC1=CC=C(C=C1)C=CCO)C
Standard InChIKey ROCWIPIJKMWFFA-ONEGZZNKSA-N
Standard InChI InChI=1S/C14H18O2/c1-12(2)9-11-16-14-7-5-13(6-8-14)4-3-10-15/h3-9,15H,10-11H2,1-2H3/b4-3+
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Evofolin C

The barks of Cinnamomum cassia Presl

Biological Activity of Evofolin C

Description1. Evofolin C and its acetate show strong antifungal and antibacterial activity. 2. Evofolin C exhibits potent inhibition against N-formylmethionylleucylphenylalanine-induced superoxide production with IC(50) values less than 12 microM.
TargetsImmunology & Inflammation related | Antifection

Evofolin C Dilution Calculator

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Evofolin C Molarity Calculator

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Preparing Stock Solutions of Evofolin C

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.5811 mL 22.9053 mL 45.8106 mL 91.6212 mL 114.5265 mL
5 mM 0.9162 mL 4.5811 mL 9.1621 mL 18.3242 mL 22.9053 mL
10 mM 0.4581 mL 2.2905 mL 4.5811 mL 9.1621 mL 11.4527 mL
50 mM 0.0916 mL 0.4581 mL 0.9162 mL 1.8324 mL 2.2905 mL
100 mM 0.0458 mL 0.2291 mL 0.4581 mL 0.9162 mL 1.1453 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Evofolin C

New phenylpropenoids, bis(1-phenylethyl)phenols, bisquinolinone alkaloid, and anti-inflammatory constituents from Zanthoxylum integrifoliolum.[Pubmed:17822293]

J Nat Prod. 2007 Sep;70(9):1444-8.

Five new compounds, including two new phenylpropenoids, (R,E)-1-[4-(3-hydroxyprop-1-enyl)phenoxy]-3-methylbutane-2,3-diol (1) and 4-hydroxy-3-(3-methyl-2-butenyl)cinnamyl alcohol (2), two new bis(1-phenylethyl)phenols, 2,6-bis(1-phenylethyl)phenol (3) and 2,4-bis(1-phenylethyl)phenol (4), and a new bisquinolinone alkaloid, 18-demethylparaensidimerin C (5), together with 17 known compounds have been isolated from the stem wood of Zanthoxylum integrifoliolum. The structures of these new compounds were determined through spectral analyses including extensive 2D nuclear magnetic resonance data. Among the isolates, N-methylflindersine (7), (-)-simulanol (10), and evofolin-C (16) exhibited potent inhibition against N-formylmethionylleucylphenylalanine-induced superoxide production with IC(50) values less than 12 microM.

Prenylated phenylpropenes from Coleonema pulchellum with antimicrobial activity.[Pubmed:9272968]

Phytochemistry. 1997 Jul;45(6):1207-12.

The lipophilic root extract of Coleonema pulchellum was analysed and tested for antifungal and antibacterial activity. Eight previously undescribed prenyloxy and geranyloxy phenylpropenes, were isolated as major compounds together with the known evofolin-C as well as the lignans (+/-)-sesamin and (+/-)-prenylpiperitol, the diterpene (-)-pimara-9(11),15-dien-19-oic acid and the 2,4-decadienoic acid isobutylamide. All structures were established by spectroscopic evidence. From the new phenylpropenes, named evofolin-C-acetate, colenemol, colenemal, prenycol acetate, dehydroprenycol acetate, precolpuchol, colpuchol and colpuchol acetate, the dihydroxylated precolpuchol displayed the strongest antifungal and antibacterial activity against Cladosporium herbarum and Staphylococcus aureus, respectively.

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