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Kadsulignan L

CAS# 163660-06-8

Kadsulignan L

Catalog No. BCN3627----Order now to get a substantial discount!

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Chemical structure

Kadsulignan L

3D structure

Chemical Properties of Kadsulignan L

Cas No. 163660-06-8 SDF Download SDF
PubChem ID 44575997 Appearance Powder
Formula C23H26O7 M.Wt 414.5
Type of Compound Lignans Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC1C(C2C3=CC(=C(C(=C3C4=C(C5=C(C=C4C1O2)OCO5)OC)OC)OC)OC)C
Standard InChIKey RNIZTMIJCBCDBR-XJSVZPCESA-N
Standard InChI InChI=1S/C23H26O7/c1-10-11(2)19-13-8-15-21(29-9-28-15)23(27-6)17(13)16-12(18(10)30-19)7-14(24-3)20(25-4)22(16)26-5/h7-8,10-11,18-19H,9H2,1-6H3/t10-,11+,18-,19+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Kadsulignan L

The stems of Kadsura japonica

Biological Activity of Kadsulignan L

Description1. Kadsulignan L shows in vitro antiviral effects on hepatitis B virus. 2. Kadsulignan L shows moderate platelet-activating factor (PAF) antagonistic activities with the IC50 value of 2.6 x 10(-5) M.
TargetsPAFR | HBV

Kadsulignan L Dilution Calculator

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Kadsulignan L Molarity Calculator

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Preparing Stock Solutions of Kadsulignan L

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.4125 mL 12.0627 mL 24.1255 mL 48.2509 mL 60.3136 mL
5 mM 0.4825 mL 2.4125 mL 4.8251 mL 9.6502 mL 12.0627 mL
10 mM 0.2413 mL 1.2063 mL 2.4125 mL 4.8251 mL 6.0314 mL
50 mM 0.0483 mL 0.2413 mL 0.4825 mL 0.965 mL 1.2063 mL
100 mM 0.0241 mL 0.1206 mL 0.2413 mL 0.4825 mL 0.6031 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Kadsulignan L

Lignans from Kadsura angustifolia.[Pubmed:11261213]

J Asian Nat Prod Res. 1998;1(2):125-31.

A new dibenzocyclooctadiene lignan named angustifolin D (1) together with four known lignans: Kadsulignan L (2), kadsulignan N (3), schisantherin P (4) and meso-dihydroguaiaretic acid (5) were isolated from the stems of Kadsura angustifolia. Their structures and stereochemistries were elucidated by spectral studies. Compounds 2 and 5 showed moderate platelet-activating factor (PAF) antagonistic activities with IC50 values of 2.6 x 10(-5) and 4.1 x 10(-5) M, respectively.

Dibenzocyclooctane lignans from the stems of Kadsura induta and their antiviral effect on hepatitis B virus.[Pubmed:17511012]

Chem Biodivers. 2007 May;4(5):966-72.

Two new dibenzocyclooctane lignans, kadsurindutins A (1) and B (2), were isolated from the stems of Kadsura induta, together with the known, structurally related lignans schisantherin L (3), schisantherin P (4), Kadsulignan L (5), and neokadsuranin (6). Their structures and configurations were elucidated by spectroscopic methods (UV, ORD, CD, IR, 1D- and 2D-NMR) in combination with mass-spectrometric (HR-MS) techniques. Compounds 1, 5, and 6 showed in vitro antiviral effects on hepatitis B virus.

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