Products with Antibacterial bioactivity

Cat.No. Product Name
BCN5056 Guaijaverin
Guaijaverin is a urease inhibitor, it (IC(50)=0.18 microM) shows an inhibitory effect on rat lens aldose reductase. Guaijaverin has antioxidant, hypoglycemic activity and inhibitory capacity against free fatty acid release.It demonstrates high potential antiplaque agent by inhibiting the growth of the Strep. Mutans.
BCN5060 9-Hydroxy-alpha-lapachone
1. 9-Hydroxy-alpha-lapachone can highly inhibit the growth of H. pylori , it exhibits potent inhibitory activity against H. pylori Cystathionine gamma-synthase, with IC(50) values of 4.64 microM. 2. 9-Hydroxy-alpha-lapachone exhibits potent inhibitory effects on lipopolysaccharide- induced NO synthesis in RAW 264.7 cells, with IC50 values of 4.64 microM, suggests that it may have anti-inflammatory activity.
BCN5062 3,8-Di-O-methylellagic acid
3,3'-Di-O-methylellagic acid reveals moderate antibacterial activity, it also shows strong DPPH radical scavenging activities with SC50 of 123.3 ug/mL. It has a lower capacity of stimulating murine peritoneal macrophages to release nitric oxide and tumoural-alpha necrose factor. 3,3'-Di-O-methylellagic acid may be a useful as pharmacological agent for the treatment of neurodegenerative diseases.
BCN5065 Falcarindiol
Falcarindiol has antimutagenic, neuroprotective, antifungal, anti-bacterial, and anticancer activities, it could be potentially used in food manufactures and cosmetology as preservative agents and biopesticides, or in medicine as new antibiotics. Falcarindiol has protective effects against CCl(4) toxicity, in part, the effects might be explained by anti-lipid peroxidation activity associated with the induction of the GSTs including GSTA4.
BCN5066 Ocotillone
Ocotillone has potent antibacterial activity against Gram-negative bacteria, P. aeruginosa and S. typhimurium, that are without hemolytic activity, whereas it has weak antimicrobial activity against Gram-positive bacteria and fungi. Ocotillone shows only weak inhibitory activity against MCF-7 and NCI-H460 cells but moderate activity against A375-C5 cells.

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