Products with Antibacterial bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5309 | Vestitol |
| Vestitol is a phytoalexin with insect feeding-deterrent activity, it has antioxidant, anti-inflammatory and antimicrobial activities, it can inhibit neutrophil migration at a dose of 10 mg/kg, and shows MICs ranging from 25-50 to 50-100 ug/mL and MBCs ranging from 25-50 to 50-100 ug/mL.Vestitol exerts a limited inhibitory effect on S. hermonthica germination, it can significantly inhibit seedling growth, it also contributes, at least in part, to the host's defence mechanism and acts as a chemical barrier against the intrusion of the parasite. | |
| BCN5321 | 6-Hydroxystigmasta-4,22-dien-3-one |
| 1. 6β-Hydroxystigmasta-4,22-dien-3-one exhibits in vitro antibacterial activity. 2. 6β-Hydroxystigmasta-4,22-dien-3-one shows antioxidant activity, the value of IC50 toward DPPH is 233.4 ± 0.28 uM. | |
| BCN5333 | Ginkgolic acid C13:0 |
| Ginkgolic acid C13:0 has a wide antimicrobial spectrum against E.coli and bacillus subtilis who are bacterias, and penicillium, penicillum purpurogenum, penicillium camemberti and aspergillus niger who are fungis, and the MIC of it against E.coli, bacillus subtilis and penicillium is 7.5, 15, 25 mg/mL seperately. It is a natural anticariogenic agent in that it exhibits antimicrobial activity against S. mutans and suppresses the specific virulence factors associated with its cariogenicity. Ginkgolic acid C13:0 exhibits the high α-glucosidase inhibitory activity; Ginkgolic acid C13:0 represents a new kind of molluscicide agent , it has a pronounced effect on snail mitochondria with gross ultrastructural changes. | |
| BCN5334 | Ginkgolic acid C17:1 |
| Ginkgolic acid C17:1 can significantly inhibit enterohemorrhagic Escherichia coli O157:H7(EHEC) biofilm formation on the surfaces of polystyrene and glass, and on nylon membranes. | |
| BCN5356 | Miltirone |
| Miltirone is a CYPs inhibition, it has been characterized as a low-affinity ligand for central benzodiazepine receptors, it might ameliorate the symptoms associated with discontinuation of long-term administration of ethanol or of other positive modulators of the GABA A receptor. Miltirone possesses significant anticancer, antibacterial, antioxidant, and anti-inflammatory activities, the hepatocyte metabolism is the major route of clearance for miltirone. Miltirone is collateral sensitive in multidrug-resistant P-gp-overexpressing cells, induces G2/M arrest, and triggeres apoptosis via ROS-generated breakdown of MMP and DNA damage. Miltirone has antiprotozoal activity against T. brucei rhodesiense STIB 900. | |
