6-Hydroxystigmasta-4,22-dien-3-oneCAS# 36450-01-8 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 36450-01-8 | SDF | Download SDF |
| PubChem ID | 71307323 | Appearance | Powder |
| Formula | C29H46O2 | M.Wt | 426.7 |
| Type of Compound | Steroids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (8S,9S,10R,13R,14S,17R)-17-[(E,2R,5S)-5-ethyl-6-methylhept-3-en-2-yl]-6-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one | ||
| SMILES | CCC(C=CC(C)C1CCC2C1(CCC3C2CC(C4=CC(=O)CCC34C)O)C)C(C)C | ||
| Standard InChIKey | FFKIQLXJMQUBQZ-NNPYVHNCSA-N | ||
| Standard InChI | InChI=1S/C29H46O2/c1-7-20(18(2)3)9-8-19(4)23-10-11-24-22-17-27(31)26-16-21(30)12-14-29(26,6)25(22)13-15-28(23,24)5/h8-9,16,18-20,22-25,27,31H,7,10-15,17H2,1-6H3/b9-8+/t19-,20-,22+,23-,24+,25+,27?,28-,29-/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Hedyotis diffusa
| Description | 1. 6β-Hydroxystigmasta-4,22-dien-3-one exhibits in vitro antibacterial activity. 2. 6β-Hydroxystigmasta-4,22-dien-3-one shows antioxidant activity, the value of IC50 toward DPPH is 233.4 ± 0.28 uM. |
| Targets | Antifection |
6-Hydroxystigmasta-4,22-dien-3-one Dilution Calculator
6-Hydroxystigmasta-4,22-dien-3-one Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.3436 mL | 11.7178 mL | 23.4357 mL | 46.8713 mL | 58.5892 mL |
| 5 mM | 0.4687 mL | 2.3436 mL | 4.6871 mL | 9.3743 mL | 11.7178 mL |
| 10 mM | 0.2344 mL | 1.1718 mL | 2.3436 mL | 4.6871 mL | 5.8589 mL |
| 50 mM | 0.0469 mL | 0.2344 mL | 0.4687 mL | 0.9374 mL | 1.1718 mL |
| 100 mM | 0.0234 mL | 0.1172 mL | 0.2344 mL | 0.4687 mL | 0.5859 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Antibacterial activity and cytotoxicity of extractives from Uvaria hamiltonii stem bark.[Pubmed:12628415]
Fitoterapia. 2003 Feb;74(1-2):159-63.
The extracts as well as piperolactum C, goniopedaline, 6beta-hydroxystigmasta-4,22-dien-3-one and a mixture of cis- and trans-4-hydroxymelleins obtained from Uvaria hamiltonii stem bark exhibited mild to moderate in vitro antibacterial activity. The results obtained were compared with a standard antibiotic, kanamycin. In a brine shrimp lethality bioassay the pet-ether, dichloromethane, methanol extracts and a major alkaloid, piperolactum C were found to exhibit mild to moderate cytotoxicity.
[Chemical constituents from Hedyotis diffusa].[Pubmed:19624011]
Zhongguo Zhong Yao Za Zhi. 2009 Mar;34(6):712-4.
OBJECTIVE: To investigate the chemical constituents from Hedyotis diffusa. METHOD: The compounds were isolated and purified by various chromatographic techniques and identified by their physicochemical properties and spectral data. RESULT: Eight compounds had been reported in last paper, and this time eight more compounds were isolated and identified as 6-Hydroxystigmasta-4,22-dien-3-one (1), 3-hydroxystigmasta-4,22-dien-7-one (2), 2-hydroxy-3-methylanthraquinone (3), 2,6-dihydroxy-3-methyl-4-methoxyanthraquinone (4), iso-scutellarein (5), isoetin (6), aesculetin (7), gypsogenic acid (8). CONCLUSION: Compounds 1-3, 5-8 were obtained from the genus Hedyotis for the first time.
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