Oxyphyllenone ACAS# 363610-34-8 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 363610-34-8 | SDF | Download SDF |
| PubChem ID | 10262534 | Appearance | Powder |
| Formula | C12H18O3 | M.Wt | 210.27 |
| Type of Compound | Sesquiterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (4aR,7R,8R)-7,8-dihydroxy-4a,8-dimethyl-4,5,6,7-tetrahydro-3H-naphthalen-2-one | ||
| SMILES | CC12CCC(C(C1=CC(=O)CC2)(C)O)O | ||
| Standard InChIKey | ORLGUEREMYIFNG-GRYCIOLGSA-N | ||
| Standard InChI | InChI=1S/C12H18O3/c1-11-5-3-8(13)7-9(11)12(2,15)10(14)4-6-11/h7,10,14-15H,3-6H2,1-2H3/t10-,11+,12-/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Oxyphyllenone A can inhibit the NO production in lipopolysaccharide-activated macrophages. |
| Targets | NO |
Oxyphyllenone A Dilution Calculator
Oxyphyllenone A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.7558 mL | 23.779 mL | 47.5579 mL | 95.1158 mL | 118.8948 mL |
| 5 mM | 0.9512 mL | 4.7558 mL | 9.5116 mL | 19.0232 mL | 23.779 mL |
| 10 mM | 0.4756 mL | 2.3779 mL | 4.7558 mL | 9.5116 mL | 11.8895 mL |
| 50 mM | 0.0951 mL | 0.4756 mL | 0.9512 mL | 1.9023 mL | 2.3779 mL |
| 100 mM | 0.0476 mL | 0.2378 mL | 0.4756 mL | 0.9512 mL | 1.1889 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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[The compounds from n-butanol fraction of Alpinia oxyphylla].[Pubmed:25757283]
Yao Xue Xue Bao. 2014 Nov;49(11):1569-73.
Nine compounds were isolated from the n-butanol fraction of 95% ethanol extract of the fruit of Alpinia oxyphylla Miq. with a combination of various chromatographic approaches, including MDS resin, silica gel, reverse phase C18 and preparative HPLC. On the basis of spectroscopic data analysis, they were elucidated as (1R, 4R, 10R)-1beta, 4alpha-dihydroxy-11, 12, 13-trinor-5, 6-eudesmen-7-one (1), 1beta, 4beta-dihydroxy-11, 12, 13-trinor-8, 9-eudesmen-7-one (2), Oxyphyllenone A (3), oxyphyllenone B (4), rhamnocitrin (5), staphylionoside D (6), benzyl-1-O-beta-D-glucopyranoside (7), 2-O-beta-D-glucopyranosyl-(1S)-phenylethylene glycol (8), and (S)-1-phenylethyl-beta-D-glucopyranoside (9). Among them, compound 1 is a new sesquiterpene, named as oxyphyllenone C; compounds 8 and 9 are new natural products; compounds 2 and 6 were isolated from the genus Alpinia for the first time, and compound 7 was isolated from A. oxyphylla for the first time.
Absolute stereostructures of novel norcadinane- and trinoreudesmane-type sesquiterpenes with nitric oxide production inhibitory activity from Alpinia oxyphylla.[Pubmed:11514174]
Bioorg Med Chem Lett. 2001 Aug 20;11(16):2217-20.
Novel 14-norcadinane-type sesquiterpenes, oxyphyllenodiols A and B, and 11,12,13-trinoreudesmane-type sesquiterpenes, oxyphyllenones A and B, were isolated from the methanolic extract of kernels of Alpinia oxyphylla. The absolute stereostructures of these norsesquiterpenes were determined on the basis of physicochemical and chemical evidence. In addition, oxyphyllenodiol A and Oxyphyllenone A were found to inhibit the NO production in lipopolysaccharide-activated macrophages.
