Ginsenoside Rk2

CAS# 364779-14-6

Ginsenoside Rk2

Catalog No. BCN3721----Order now to get a substantial discount!

Product Name & Size Price Stock
Ginsenoside Rk2: 5mg $230 In Stock
Ginsenoside Rk2: 10mg Please Inquire In Stock
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Ginsenoside Rk2: 200mg Please Inquire Please Inquire
Ginsenoside Rk2: 500mg Please Inquire Please Inquire
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Quality Control of Ginsenoside Rk2

Number of papers citing our products

Chemical structure

Ginsenoside Rk2

3D structure

Chemical Properties of Ginsenoside Rk2

Cas No. 364779-14-6 SDF Download SDF
PubChem ID 90472238 Appearance Powder
Formula C36H60O7 M.Wt 604.9
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-(6-methylhepta-1,5-dien-2-yl)-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-3,4,5-triol
SMILES CC(=CCCC(=C)C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)OC5C(C(C(C(O5)CO)O)O)O)C)C)O)C)C
Standard InChIKey WMGBQZAELMGYNO-YMWSGFAJSA-N
Standard InChI InChI=1S/C36H60O7/c1-20(2)10-9-11-21(3)22-12-16-36(8)28(22)23(38)18-26-34(6)15-14-27(33(4,5)25(34)13-17-35(26,36)7)43-32-31(41)30(40)29(39)24(19-37)42-32/h10,22-32,37-41H,3,9,11-19H2,1-2,4-8H3/t22-,23-,24-,25+,26-,27+,28+,29-,30+,31-,32+,34+,35-,36-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Ginsenoside Rk2

The roots of Panax ginseng C. A. Mey.

Biological Activity of Ginsenoside Rk2

DescriptionGinsenoside Rk1 has anti-tumor, and anti-platelet aggregation activities. Ginsenoside Rk1 can strongly inhibit permeability induced by VEGF, advance glycation end-product, thrombin, or histamine in human retinal endothelial cells, it reduces the vessel leakiness of retina in a diabetic mouse model; this anti-permeability activity of Rk1 is correlated with enhanced stability and positioning of tight junction proteins at the boundary between cells; Rk1 induces phosphorylation of myosin light chain and cortactin, which are critical regulators for the formation of the cortical actin ring structure and endothelial barrier.
TargetsVEGFR
In vitro

Three new dammarane glycosides from heat processed ginseng.[Pubmed: 12214849]

Arch Pharm Res. 2002 Aug;25(4):428-32.

Three new dammarane glycosides were isolated from the processed ginseng (SG; Sun Ginseng).
METHODS AND RESULTS:
Their structure were determined to be 3beta,12beta-dihydroxydammar-20(21),24-diene-3-O-beta-D-glucopyranosyl(1 --> 2)-beta-D-glucopyranoside; 3beta,12beta-dihydroxydammar-20(21),24-diene-3-O-beta-D- glucopyranoside and 3beta,6alpha,12beta-trihydroxydammar-20(21),24-diene-6-O-beta-D-glucopyranoside based on spectroscopic evidences.
CONCLUSIONS:
The compounds were named as Ginsenoside Rk1, Ginsenoside Rk2, and ginsenoside Rk3 respectively.

Ginsenoside Rk2 Dilution Calculator

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Ginsenoside Rk2 Molarity Calculator

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Preparing Stock Solutions of Ginsenoside Rk2

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.6532 mL 8.2658 mL 16.5317 mL 33.0633 mL 41.3291 mL
5 mM 0.3306 mL 1.6532 mL 3.3063 mL 6.6127 mL 8.2658 mL
10 mM 0.1653 mL 0.8266 mL 1.6532 mL 3.3063 mL 4.1329 mL
50 mM 0.0331 mL 0.1653 mL 0.3306 mL 0.6613 mL 0.8266 mL
100 mM 0.0165 mL 0.0827 mL 0.1653 mL 0.3306 mL 0.4133 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Ginsenoside Rk2

Three new dammarane glycosides from heat processed ginseng.[Pubmed:12214849]

Arch Pharm Res. 2002 Aug;25(4):428-32.

Three new dammarane glycosides were isolated from the processed ginseng (SG; Sun Ginseng). Their structure were determined to be 3beta,12beta-dihydroxydammar-20(21),24-diene-3-O-beta-D-glucopyranosyl(1 --> 2)-beta-D-glucopyranoside; 3beta,12beta-dihydroxydammar-20(21),24-diene-3-O-beta-D- glucopyranoside and 3beta,6alpha,12beta-trihydroxydammar-20(21),24-diene-6-O-beta-D-glucopyranoside based on spectroscopic evidences. The compounds were named as ginsenoside Rk1, Rk2, and Rk3 respectively.

Description

Ginsenoside Rk2 is a dammarane glycoside isolated from the processed ginseng (SG; Sun Ginseng).

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