Emiline

CAS# 36506-99-7

Emiline

Catalog No. BCN2080----Order now to get a substantial discount!

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Quality Control of Emiline

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Chemical structure

Emiline

3D structure

Chemical Properties of Emiline

Cas No. 36506-99-7 SDF Download SDF
PubChem ID 169779 Appearance Powder
Formula C19H27NO6 M.Wt 365.42
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CCC1CC(=C)C(C(=O)OCC2=CC[N+]3(C2(C(CC3)OC1=O)O)C)(C)O
Standard InChIKey NJNQFHVIXUJHSN-FBHNOXKOSA-N
Standard InChI InChI=1S/C19H28NO6/c1-5-13-10-12(2)18(3,23)17(22)25-11-14-6-8-20(4)9-7-15(19(14,20)24)26-16(13)21/h6,13,15,23-24H,2,5,7-11H2,1,3-4H3/q+1/t13?,15-,18?,19?,20?/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of Emiline

Description1. (±)-Emiline displays good neuroprotective effect against the corticosterone-induced apoptosis in PC12 cells.

Emiline Dilution Calculator

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Emiline Molarity Calculator

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Preparing Stock Solutions of Emiline

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7366 mL 13.6829 mL 27.3658 mL 54.7315 mL 68.4144 mL
5 mM 0.5473 mL 2.7366 mL 5.4732 mL 10.9463 mL 13.6829 mL
10 mM 0.2737 mL 1.3683 mL 2.7366 mL 5.4732 mL 6.8414 mL
50 mM 0.0547 mL 0.2737 mL 0.5473 mL 1.0946 mL 1.3683 mL
100 mM 0.0274 mL 0.1368 mL 0.2737 mL 0.5473 mL 0.6841 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Emiline

Senecipyrrolidine, an unusual pyrrolidine alkaloid isolated from Jacobaea gigantea (Desf.) Pelser (Asteraceae).[Pubmed:30375240]

Nat Prod Res. 2018 Oct 30:1-10.

Alkaloids and phenolic compounds are among the most biologically active natural products from the Jacobaea/Senecio genera (Asteraceae). To isolate original natural products directly from Jacobaea gigantea crude polar extracts, centrifugal partition chromatography (CPC) was used. Previously, we reported the phytochemical study of J. gigantea (syn. Senecio giganteus) n-butanol extract using various classical chromatographical techniques combined with CPC. Herein major constituents from the J. gigantea crude ethyl acetate extract and further compounds from the n-butanol extract were purified in only one step using this technique. A new pyrrolidine alkaloid, named senecipyrrolidine was isolated along with thirteen known compounds - chiro-inositol, three phenolic acids, six flavonoids, two quinones and Emiline, another pyrrolidine alkaloid - from crude n-butanol or ethyl acetate extracts. Pyrrolidine alkaloids were isolated for the first time in the Jacobaea/Senecio genera and were probably biogenetically related to the two isolated quinones derivatives jacaranone and 3a-hydroxy-3,3a,7,7a-tetrahydrobenzofuran-2,6-dione, isolated in this species.

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