Products with Antibacterial bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1662 | De-4'-O-methylyangambin |
| 1. De-4'-O-methylyangambin has analgesia activity. 2. De-4'-O-methylyangambin exhibits antibacterial effects. | |
| BCN1665 | Marmin |
| 1. Marmin can inhibit contraction of the guinea-pig tracheal smooth muscle, especially by interfering histamine receptor, inhibiting the histamine release from mast, inhibiting intracellular Ca2+ release from the intracellular store and the Ca2+ influx through voltage-dependent Ca2+ channels. 2. Marmin, skimmianine, aegeline, aurapten, zeorin, and dustanin are potential to develop as antihistamine agents, especially as histamine H1 receptor antagonists by interacting with amino acid residues, Asp107, Lys179, Lys191, Asn198, and Trp428 of histamine H1 receptor. 3. S-trans-Marmin shows potent antibacterial, fungicidal, and algicidal properties. 4. Marmin shows a cell-growth inhibitory effect against L1210 and K562 in vitro. 5. Marmin and nobiletin have anti-ulcer effects, which are ascribed primarily to the maintenance of the mucosal barrier integrity and inhibition of gastric motor activity and secondarily due to the prevention of the effects of endogenous acetylcholine and histamine. | |
| BCN1666 | Chrysosplenol D |
| Chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials. Chrysosplenol D has anti-inflammatory, antimalarial, antibacterial and antifungal activities; it also exerts its anti-proliferative effect on tsFT210 cells through inhibiting cell cycle and inducing apoptosis, it may as a new cell cycle inhibitor. | |
| BCN1673 | Phytol |
| Phytol, a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal fields, shows antinociceptive, antioxidant ,anti-inflammatory, antimicrobial, antileishmanial, cytotoxicity and antiallergic effects. It is a specific activator of PPARα, it interacts with GABAA receptor, probably at the receptor subtypes that mediate benzodiazepines effects. Phytol attenuates the inflammatory response by inhibiting neutrophil migration that is partly caused by reduction in IL-1β and TNF-α levels and oxidative stress. | |
| BCN1691 | 3,5-Dihydroxy-4',7-dimethoxyflavone |
| 1. 3,5-Dihydroxy-4',7-dimethoxyflavone shows antioxidant activity, it also shows significant activity against Staphylococcus aureus and Escherichia coli with minimum inhibitory concentration (MIC) at 200 ug/ml and 225 ug/ml, respectively. | |
