Products with Antibacterial bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1853 | Pramanicin |
| 1. Pramanicin, an antifungal agent, has vasorelaxant effect, it induces a slow endothelium-dependent relaxation, which could be reversed with the NO synthase inhibitor, L-NOARG . 2. Pramanicin has potent, selective, and irreversible inhibitory effect on the endothelial , thus it has potential development into an anti-angiogenic drug. 3. Pramanicin causes an initial slow endothelium-dependent, NO-mediated vascular relaxation, followed by a cytotoxic effect on vascular endothelial cells, eventually resulting in the loss of vasorelaxant function. 4. Pramanicin as a potential apoptosis-inducing small molecule, which acts through a well-defined JNK- and p38-dependent apoptosis signalling pathway in Jurkat T leukemia cells. 5. Pramanicin is an antimicrobial agent . | |
| BCN1855 | Reutericyclin |
| 1. Reutericyclin is a unique antimicrobial tetramic acid produced by some strains of Lactobacillus reuteri. 2. Reutericyclin and nisin exhibit divergent effects on heat- and pressure-induced spore inactivation and membrane fluidity. 3. Dissipation of the membrane potential by active Reutericyclins correlated with inhibition of macromolecular synthesis in cells. 4. All reutericyclins can inhibit the growth of clinical isolates of drug-resistant Staphylococcus aureus, which exemplify the prospect of developing reutericyclins as new topical antibiotics. | |
| BCN1858 | Streptolydigin |
| 1. Streptolydigin has antibacterial activity against a number of Gram positive bacteria. 2. Streptolydigin inhibits RNA polymerase by sequestering the active center in a catalytically inactive conformation. | |
| BCN1860 | Tirandalydigin |
| 1. Tirandalydigin is a new tetramic acid antibiotic, it has MICs in the range of 0.5 to 32 micrograms/ml against many pathogenic anaerobes, streptococci, enterococci and legionellae. | |
| BCN1862 | Tirandamycin B |
| 1. Tirandamycin B is a BmAsnRS inhibitor. 2. Tirandamycin B is a leading anti-filarial drug . 3. Tirandamycin B has antitumor and antibacterial activities. | |
