Products with Antibacterial bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2218 | Sorbic acid |
| Sorbic acid is important food preservatives and powerful fungistatic agents, it inhibits various bacteria, including sporeformers, at various stages of their life cycle (germination, outgrowth and cell division). Sorbic acid is a more potent uncoupler of the membrane potential than acetic acid, the effect may also slow the rate of ATP synthesis significantly and may thus (partially) explain Sorbic acid's effectiveness. | |
| BCN2282 | Demethylzeylasteral |
| Demethylzeylasteral exhibits strong inhibition towards UDP-glucuronosyltransferase (UGT) 1A6 and 2B7, and the inhibition kinetic parameters (Ki) are calculated to be 0.6 uM and 17.3 uM for UGT1A6 and UGT2B7, respectively. Demethylzeylasteral has antimicrobial, strong immunosuppressive, and antifertility activities; it concentration-dependently and in a partially reversible manner can inhibit the Ca(2+) current in spermatogenic cells with an IC(50) of 8.8 microg/ml, and it also can inhibit significantly the sperm acrosome reaction initiated by progesterone. | |
| BCN2307 | Ginkgolic acid C15:1 |
| Ginkgolic acid C15:1 has antibacterial, antiparasitic, and anti-cancer activities, it can suppress lung cancer invasion and migration through the inhibition of PI3K/Akt/mTOR signaling pathway. | |
| BCN2308 | Dihydroisotanshinone I |
| Dihydroisotanshinone I has protective action against menadione-induced hepatotoxicity, attributed to its antioxidant properties including the free radical scavenging activity and inhibition of lipid peroxidation. | |
| BCN2327 | Isofraxidin |
| Isofraxidin has definite anti-bacterial, anti-oxidant, analgesic,and anti-inflammatory activities, it inhibits expression of MMP-7 and in vitro cell invasion at a non-toxic level through inhibiting ERK1/2 phosphorylation in hepatoma cell lines.Isofraxidin is one possible radio-protector, it can protect leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. | |
