Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5848 | Phyllanthin |
| 1. Phyllanthin is widely used as hepatoprotective and antigenotoxic and inhibit function of P-gp. | |
| BCN5854 | Nodosin |
| 1. Nodosin has anti-inflammatory function of Nodosin via inhibition of IL-2. 2. Nodosin perfusion provides a potential protective effect through inducing HO-1 expression to attenuate ischemia/reperfusion injury in liver transplantation. | |
| BCN5861 | Ganoderic acid S |
| A novel combination of triterpenoids includes at least ganoderic acid S (GAS), ganoderic acid T (GAT), ganoderic acid Me (GAMe), ganoderic acid R (GAR), and ganodermic acid S (GMAS), the composition is suitable for the treatment or prophylaxis of colon cancer, hepatic cancer, breast cancer, lung cancer or leukemia. Ganoderic acid S and Mf induce mitochondria mediated apoptosis in human cervical carcinoma HeLa cells. | |
| BCN5862 | 3alpha-Akebonoic acid |
| 1. 3α-Akebonoic acid shows interesting in vitro growth inhibitory activity against human tumor A549 and HeLa cell lines, it also shows significant in vitro α-glucosidase inhibitory activity. 2. 3α-Akebonoic acid can interfer with presenilin-1 (PS1)/ β-site APP-cleaving enzyme 1 (BACE1) interaction and reduces Aβ production, the chemical interference of PS1/BACE1 interaction is a promising strategy for Alzheimer’s disease therapeutics. | |
| BCN5872 | Ganodermanontriol |
| Ganodermanontriol has anti-cancer, hepatoprotective, anti-inflammatory, and antioxidative activities, it also shows a strong anticomplement activity against the classical pathway (CP) of the complement system with IC(50) values of 17.2 microM. Ganodermanontriol is active as an anti-HIV-1 agent with an inhibitory concentration of 7.8 micrograms ml-1.It has a wide spectrum of targets including HO-1, PI3K/Akt and p38 kinases. | |
