Products with Anticancer Bioactivity

Explore BioCrick products associated with Anticancer biological activity, including catalog numbers, product names and available bioactivity information.

Cat. No.	Product Name
BCN5757	Eichlerianic acid
1. Eichlerianic acid shows weak cytotoxicity (IC50 6.87 to >40 μM) against human cancer cell (HL-60, SMMC-7721, A-549, MCF-7 and SW480). 2. Eichlerianic acid is a trypanocidal compound with an IC50 value of 10 mg/mL. 3. Eichlerianic acid may have antiviral activity against Herpes simplex virus types I and II in vitro.
BCN5763	Tanshinone IIA
Tanshinone IIA is an estrogen receptor partial agonist with antiandrogenic properties, it has neuroprotective effects against cerebral ischemia/reperfusion injury and traumatic injury of the spinal cord in rats. Tanshinone IIA has anti-leukemia, anti-inflammatory and anti-oxidative properties, inhibits the release of inflammatory cytokines, such as, IL-1 β, IL-6 α, TNF-α.
BCN5764	Tanshinone I
Tanshinone I is an inhibitor of type IIA human recombinant sPLA2 (IC50=11 μM) and rabbit recombinant cPLA2 (IC50=82 μM). Tanshinone I possesses hepatocyte protective, anticancer, neuroprotection, and nephroprotective properties. Tanshinone I pretreatment causes significant suppression of skin cell death induces by solar simulated UV and riboflavin-sensitized UVA.
BCN5767	Penduletin
1. Penduletin shows anti- tumor cells activity. 2. Penduletin significantly reduces TGF-β1 production. 3. Penduletin has strong activity in vitro against EV71 with low cytotoxicity. 4. Penduletin inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. 5. Penduletin may have anti-inflammatory activity, it can partially inhibit synovial phospholipase A2 activity.
BCN5768	Xanthohumol
Xanthohumol has anti-hepatitis C virus, anti-carcinogenic, free radical-scavenging, and anti-inflammatory activities, it can inhibit HIV-1 induced cytopathic effects, the production of viral p24 antigen and reverse transcriptase in C8166 lymphocytes at non-cytotoxic concentration. Xanthohumol may play a role in improving cognitive flexability in young animals. Xanthohumol has beneficial effects on markers of metabolic syndrome, it lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats.Valosin-containing protein (VCP) inhibitor. Binds to the N domain of VCP, impairing autophagosome function and maturation. Inhibits proliferation and induces apoptosis in a variety of human cancer cell lines. Also inhibits DGAT in rat liver microsomes (IC<sub>50</sub> = 50.3 <span class='symbol'>μ</span>M).

Anticancer Bioactivity Products