Products with Antioxidants bioactivity

Cat.No. Product Name
BCN5716 Corylin
Corylin has a variety of pharmacological effects such as antioxidant, anti-proliferation, and anti-inflammatory properties, it may stimulate bone formation or have potential activity against osteoporosis. Corylin shows an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells.
BCN5717 Aristolactam BII
1. Aristolactam BII exerts its significant neuroprotective effects on glutamate-injured primary cultures of rat cortical cells by directly inhibiting the production of nitric oxide. 2. Aristolactam BII exhibits antimicrobial and antiinflammatory activity. 3. Aristolactam BII shows significant activity towards DPPH radical scavenging and potent inhibitory effects against tyrosinase mushroom.
BCN5725 Lupeol
1. Lupeol has a potential to act as an anti-inflammatory, anti-microbial, anti-protozoal, anti-proliferative, anti-invasive, anti-angiogenic, antimalarial and cholesterol lowering agent. 2. Lupeol prevents acetaminophen-induced in vivo hepatotoxicity by altering the Bax/Bcl-2 and oxidative stress-mediated mitochondrial signaling cascade. 3. Lupeol and its ester derivative have beneficial effects on hypercholesterolemia-induced oxidative and inflammatory stresses. 4. Lupeol significantly enhances the radiosensitivity of SMMC-7721 cells in vitro and in vivo. 5. Lupeol shows antidiabetic and antioxidant potential in experimental hyperglycaemia. 6. Lupeol has potential anticancer effect against hepatocellular and pancreatic cancer, by inhibiting cell proliferation, inducing apoptosis and blocking Akt/PI3K and Wnt signaling pathway. 7. Lupeol has antiangiogenic effects, it (at 50 and 30 microg/mL) shows a marked inhibitory activity on human umbilical venous endothelial cells (HUVEC) tube formation while it does not affect the growth of tumor cell lines such as SK-MEL-2, A549, and B16-F10 melanoma.
BCN5728 Roseoside
1. Roseoside (vomifoliol glucosides) exhibits inhibitory activity on leukotriene release from mouse bone marrow-derived cultured mast cells (BMCMC). 2. (6S,9R)-Roseoside can inhibit the histamine release from rat peritoneal exudate cells induced by antigen-antibody reaction. 3. Roseoside possesses strong antioxidant properties, inhibiting lipid oxidation by 86.4, at 50 microg/mL. 4. Roseoside has insulinotropic activity, enhances insulin release from the β-cell line INS-1. 5. Roseoside can significantly delay carcinogenesis induced by peroxynitrite (initiator) and TPA (promoter).
BCN5729 Pinobanksin
1. Pinobanksin possesses considerable antimutagenic properties against ofloxacin-induced bleaching of E. gracilis. 2. Pinobanksin and some of its ester derivatives from Sonoran propolis have apoptotic induction in a B-cell lymphoma cell line. 3. Pinobanksin inhibits peroxidation of low density lipoprotein and it has electron donor properties reducing alpha-tocopherol radicals.

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