Products with Antioxidants bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN6758 | Urolignoside |
| 1. Urolignoside shows antioxidant and radical scavenging activities. | |
| BCN6770 | Brandioside |
| 1. Brandioside exhibits significant inhibition of advanced glycation end product formation with the IC50 value of 4.6-25.7 uM. 2. Brandioside significantly attenuates glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 microM. 3. Brandioside shows inhibition of smooth muscle cell proliferation, indicates that it may have preventative effects on arteriosclerosis. 4. Brandioside shows strong antioxidant effect. | |
| BCN6789 | Alloisoimperatorin |
| Alloisoimperatorin is a candidate of AChE inhibitors, it displays potent antioxidant effects against the DPPH radical and against renal epithelial cell injury by using AAPH to generate peroxyl radicals in vitro. Alloisoimperatorin has estrogenic activity on the Ishikawa cell line, it shows strong ability to induce alkaline phosphatase (AP) with the EC50 values of 0.8 microg/mL. | |
| BCN6790 | Dehydroglyasperin C |
| 1. Dehydroglyasperin C exhibits cancer chemopreventive potential via its inhibitory effect on TPA-induced neoplastic cell transformation and COX-2 modulation through regulation of the MKK4 and PI3K pathways. 2. Dehydroglyasperin C may inhibit microglia hyperactivation by increasing MKP-1 expression and acting as a potent anti-neurodegenerative agent. 3. Dehydroglyasperin C possesses potent antioxidant activity, suggests that it has protective effects against chronic diseases caused by reactive oxygen species as well as potential as an antioxidant food additive. 4. Dehydroglyasperin C can attenuate proliferation and migration induced by platelet-derived growth factor in human arterial smooth muscle cells. 5. Dehydroglyasperin C protects neuronal cells against glutamate-induced oxidative injury through the induction of HO-1 expression, which is, in turn, activated maybe through Nrf2-Keap1 and PI3K/AKT signaling pathways. 6. Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. | |
| BCN6796 | Mosloflavone |
| 1. Mosloflavanone is an antifungal and radical scavenging 2-hydroxyflavanone. 2. Mosloflavone possesses strong anti-EV71 activity and decreased the formation of visible cytopathic effects, it also inhibits virus replication during the initial stage of virus infection, and inhibits viral VP2 protein expression, thereby inhibiting viral capsid protein synthesis. 3. Mosloflavone can significantly prolong the survival time of hypoxic mice. 4. Mosloflavone shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 uM and 6.4 uM, respectively; it shows dose-dependent inhibition of TNF-α, IL-1β and iNOS levels in the supernatant of mouse macrophage cell line J774A. 5. Mosloflavone can be used as a starting point to discover lead structures for treatment of inflammatory and immunomodulatory diseases. | |
