Products with Antioxidants bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5732 | 2-Oxopomolic acid |
| 1. 2-Oxopomolic acid shows cytotoxic activity. 2. 2-Oxopomolic acid shows radical-scavenging activities similar to that of the reference antioxidant alpha-tocopherol (vitamin E). 3. 2-Oxopomolic acid shows a significant decrease in intracellular melanin content in B16-F10 cells, and in culture media melanin. | |
| BCN5735 | Andrographolide |
| Andrographolide is an antiinflammatory, antiviral, anti-cancer , hepatoprotective, antithrombotic, hypotensive and antiatherosclerotic drug, it can cure hyperpigmentation disorders. Andrographolide protects against chemical-induced oxidative damage by up-regulating the gene transcription and activity of antioxidant enzymes in various tissues.Andrographolide has potential as a leading compound in the prevention or treatment of obesity and insulin resistance, can ameliorate lipid metabolism and improve glucose use in mice with HFD-induced obesity. | |
| BCN5738 | Paeonol |
| Paeonol has anticancer, anti-inflammatory, antioxidant and cardiovascular protective activities, it shows a novel inhibitory role on neuroinflammation, and presents a new candidate agent for the development of therapies for inflammation-related neurodegenerative diseases. Paeonol suppresses lipopolysaccharide-induced inflammatory cytokines in macrophage cells and protects mice from lethal endotoxin shock. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively; it inhibits PGE₂ synthesis and COX-2 expression, and modulates Sirtuin 1, PKCδ and c-Src signaling pathway. | |
| BCN5739 | Isorhoifolin |
| 1. Isorhoifolin has antioxidant effects. 2. Isorhoifolin displays an anti-leakage effect comparable to or greater than diosmin. 3. Isorhoifolin in Pilea microphylla (PM1) may reverse the disturbed metabolic milieu in C57BL/KsJ-db/db mice. 4. Isorhoifolin and vicenin II are main compounds of ethyl acetate fraction (EAcF) obtained from Erythrina velutina leaves, EAcF increases the cardiac contractile force by increasing the l-type calcium current and activating the adrenergic receptor pathway. | |
| BCN5743 | Myriceric acid B |
| 1. Myriceric acid B is a potent HIV-1 entry inhibitor targeting gp41 and can serve as a lead compound for developing novel anti-HIV-1 drug. 2. Myriceric acid B scavenges DPPH free radicals with IC50 value of 21.8 uM, it inhibits aromatase activity with IC50 value of 6.8 uM, it also exhibits cytotoxic activity towards the MOLT-3 cell line with IC50 values of 3.9 uM. | |
