Products with Bronchodilators bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2606 | Vincamine |
| Vincamine is a plant alkaloid used clinically as a peripheral vasodilator that increases cerebral blood flow and oxygen and glucose utilization by neural tissue to combat the effect of aging. Vincamine has contractile and relaxant actions on the guinea pig trachealis, may be due to the generation of prostaglandins and to changes in the membrane Ca2+ fluxes and/or the intracellular Ca2+ distribution. Vincamine alleviates Amyloid-β 25-35 peptides-induced cytotoxicity in PC12 cells. | |
| BCN3435 | Peucedanocoumarin II |
| 1. Peucedanocoumarin II shows only partial relaxation. | |
| BCN3790 | Isokaempferide |
| 1. Isokaempferide shows anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by reducing neutrophil degranulation, myeloperoxidase activity, mediators as well as TNF-alpha secretion. 2. Isokaempferide is used as a bronchodilator, can induce relaxation of guinea-pig isolated trachea. 3. The hydroxyflavones (luteolin, apigenin and isokaempferide) exert comparable antiproliferative activities against malignant and normal cells. 4. Isokaempferide shows strong inhibitory effect on TNF-alpha-induced liver cell death with the IC50 value of 22.8 microM, suggests that it has hepatoprotective activity. | |
| BCN4992 | Peimisine |
| Peimisine may have antihypertensive action, it can inhibit angiotensin I converting enzyme activity in a dose-dependent manner(the IC50 value of 526.5 microM). Peimisine can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. It plays a protective role against LPS-induced acute lung injury, and against the experimental hepatic fibrosis formation. | |
| BCN5589 | Vasicinone |
| 1. Vasicinone may act as a hepatoprotective agent. 2. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease. 3. (S)-Vasicinone exhibits antiproliferative activity against human gastric cancer cells MCG-803. | |
