Products with
Carcinogens bioactivity
Cat.No.
|
Product Name
|
BCN5439 |
Seneciphylline N-oxide
|
1. Seneciphylline N-oxide and senecionine N-oxide are probably tumorigenic due to their potential conversion into seneciphylline and senecionine via metabolic reduction in the body. |
BCN6054 |
Bis(2-ethylhexyl) phthalate
|
Bis(2-ethylhexyl) phthalate (DEHP) is a compound widely used in plastics technology to impart flexibility to rigid polymers, DEHP has oral toxicity during pregnancy and suckling in the Long-Evans rat.It can induce antiandrogenic effects in Spague-Dawley (SD) rats. |
BCN6262 |
Aristolochic acid A
|
Aristolochic acid A is a potent nephrotoxin, which strongly induced toxic damage during ovarian maturation by inhibiting Akt phosphorylation-mediated suppression of apoptosis. |
BCN6263 |
Aristolochic acid B
|
Aristolochic acid II (Aristolochic acid B,AAII), one of the major components of the carcinogenic plant extract aristolochic acid, is known to be mutagenic and to form DNA adducts in vitro and in vivo, AAII shows more carcinogenic risk than aristolochic acid I, and this may be, at least partly, the result of its increased levels in kidney and plasma. |
BCN6642 |
20-Deoxyingenol 3-angelate
|
1. 20-Deoxyingenol 3-angelate can induce significant platelet aggregation accompanied by induction of phosphorylation of PKC substrates in platelets, it is a protein kinase C (PKC) activator.
2. 20-Deoxyingenol 3-angelate and ingenol 20-acetate 3-angelate are known as promoters of tumors of mouse skin. |