Products with Cardioprotective bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2541 | Tanshinone IIA-sulfonic sodium |
| Tanshinone IIA sulfonate (sodium) is a water-soluble derivative of tanshinone IIA, which acts as an inhibitor of store-operated Ca2+ entry (SOCE), and is used to treat cardiovascular disorders.Sodium tanshinone IIA sulfonate pretreatment reduces infarct size and improves cardiac function in an ischemia-reperfusion-induced rat myocardial injury model via activation of Akt/FOXO3A/Bim-mediated signal pathway. | |
| BCN2554 | 20R-Ginsenoside Rg2 |
| Ginsenoside Rg2 may have a therapeutic potential for type 2 diabetic patients, it suppresses the hepatic glucose production via AMPK-induced phosphorylation of GSK3βand induction of SHP gene expression .Ginsenoside Rg2 can protect H9c2 cells against H2O2- induced injury through its actions of anti-oxidant and anti-apoptosis.20R-Ginsenoside Rg2 inhibits the cytokine interleukin 1 alpha (IL-1α)-induced reduction in gap junction-mediated intercellular communication (GJIC). | |
| BCN2685 | Isosteviol |
| Isosteviol possesses various biological activities including anti-hyperglycemic, anti-hypertensive, anti-tumor, anti-inflammatory, neuroprotective, antibacterial, antifungal,and antioxidant effects.Isosteviol plays a protective role in a variety of stress-induced cardiac diseases, it can prevent the prolongation of action potential in hypertrophied cardiomyoctyes by regulating transient outward potassium and L-type calcium channels. | |
| BCN2758 | Hirsutine |
| Hirsutine has anticancer, cardioprotective, anti‑hypertensive and anti-arrhythmic activities, it also has vasodilatation activity, the mechanism is related to blockade of Ca2+ influx through L-type Ca2+ channels and inhibition of intracellular Ca2+ release may have no relationship with K+ channels. Hirsutine reduces the production of various neurotoxic factors in activated microglial cells and possesses neuroprotective activity in a model of inflammation-induced neurotoxicity. | |
| BCN2787 | Calceolarioside B |
| Calceolarioside B has anti-proliferation property. | |
