Products with Central nervous system depressant action bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1520 | Quercetin 3-O-glucoside-7-O-rhamnoside |
| 1. Quercetin 3-O-glucoside-7-O-rhamnoside at 30 mg/kg i.p. can decrease the ambulatory locomotor activity and increase the sodium thiopental-induced time of loss of the righting reflex suggesting a clear depressant action. | |
| BCN2155 | Gramodendrine |
| 1. Gramodendrine and ammodendrine are moderately potent (300 mg/kg, ip) in reducing spontaneous motor activity (30% of control) and in causing central nervous system depression (50% of control). spect. | |
| BCN2160 | Sodium barbital |
| 1. Sodium barbital was used as a model non-genotoxic renal carcinogen to test whether a concentration that increased renal tubular proliferation without severe nephrotoxicity would enhance tumor induction in a hereditary tumor model. 2. Sodium barbital causes progression to the stage of spontaneous renal lesions in Tsc2 mutant rats but do not increase their overall number. 3. Sodium barbital is a depressant of the central nervous system, has sedative/hypnotic effects. 4. Sodium barbital as an inhibitor of rabbit-muscle creatine kinase (CK), it might compete with both creatine and ATP, but mainly with creatine, to inhibit the activity of CK. 5. Sodium barbital is a tumour promoter, it can shorten the otherwise long latency between exposure to toxin and tumourigenesis. | |
| BCN2233 | DL-Homocysteic acid |
| DL-Homocysteic acid application disrupts calcium homeostasis and induces degeneration of spinal motor neurons in vivo. | |
