GramodendrineCAS# 83905-67-3 |
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| Cas No. | 83905-67-3 | SDF | Download SDF |
| PubChem ID | 158591 | Appearance | Powder |
| Formula | C21H27N3O | M.Wt | 337.40 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1-[5-[1-(1H-indol-3-ylmethyl)piperidin-2-yl]-3,4-dihydro-2H-pyridin-1-yl]ethanone | ||
| SMILES | CC(=O)N1CCCC(=C1)C2CCCCN2CC3=CNC4=CC=CC=C43 | ||
| Standard InChIKey | YRVWJJHMGFKSBV-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C21H27N3O/c1-16(25)23-12-6-7-17(14-23)21-10-4-5-11-24(21)15-18-13-22-20-9-3-2-8-19(18)20/h2-3,8-9,13-14,21-22H,4-7,10-12,15H2,1H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Gramodendrine and ammodendrine are moderately potent (300 mg/kg, ip) in reducing spontaneous motor activity (30% of control) and in causing central nervous system depression (50% of control). spect. |
Gramodendrine Dilution Calculator
Gramodendrine Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.9638 mL | 14.8192 mL | 29.6384 mL | 59.2768 mL | 74.096 mL |
| 5 mM | 0.5928 mL | 2.9638 mL | 5.9277 mL | 11.8554 mL | 14.8192 mL |
| 10 mM | 0.2964 mL | 1.4819 mL | 2.9638 mL | 5.9277 mL | 7.4096 mL |
| 50 mM | 0.0593 mL | 0.2964 mL | 0.5928 mL | 1.1855 mL | 1.4819 mL |
| 100 mM | 0.0296 mL | 0.1482 mL | 0.2964 mL | 0.5928 mL | 0.741 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Gramodendrine, a bipiperidyl-indole alkaloid from Lupinus arbustus subsp. calcara tus
Phytochemistry Volume 21, Issue 6, 1982, Pages 1415-1417
A new bipiperidyl-indole alkaloid, Gramodendrine, was isolated from Lupinus arbustus subsp. calcaratus. Its structure was determined from spect.
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