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Angeloylisogomisin O

CAS# 83864-70-4

Angeloylisogomisin O

Catalog No. BCN4379----Order now to get a substantial discount!

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Chemical structure

Angeloylisogomisin O

3D structure

Chemical Properties of Angeloylisogomisin O

Cas No. 83864-70-4 SDF Download SDF
PubChem ID 91864463 Appearance Cryst.
Formula C28H34O8 M.Wt 498.6
Type of Compound Lignans Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(9S,10S,11R)-3,4,5,19-tetramethoxy-9,10-dimethyl-15,17-dioxatetracyclo[10.7.0.02,7.014,18]nonadeca-1(19),2,4,6,12,14(18)-hexaen-11-yl] (Z)-2-methylbut-2-enoate
SMILES CC=C(C)C(=O)OC1C(C(CC2=CC(=C(C(=C2C3=C(C4=C(C=C13)OCO4)OC)OC)OC)OC)C)C
Standard InChIKey PZUDCPSZWPLXKT-XXDSNBTQSA-N
Standard InChI InChI=1S/C28H34O8/c1-9-14(2)28(29)36-23-16(4)15(3)10-17-11-19(30-5)24(31-6)26(32-7)21(17)22-18(23)12-20-25(27(22)33-8)35-13-34-20/h9,11-12,15-16,23H,10,13H2,1-8H3/b14-9-/t15-,16-,23+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Angeloylisogomisin O

The fruits of Schizandra chinensis

Biological Activity of Angeloylisogomisin O

DescriptionStandard reference

Protocol of Angeloylisogomisin O

Structure Identification
Chem Pharm Bull (Tokyo). 2007 Aug;55(8):1281-3.

Lignans from Schisandra propinqua var. propinqua.[Pubmed: 17666862]


METHODS AND RESULTS:
Two new dibenzocyclooctadiene lignans angeloyl-(+)-gomisin K(3) (1) and methylisogomisin O (2), together with six known ones, isogomisin O, Angeloylisogomisin O, gomisin O, angeloygomisin O, benzoylgomisin O, epigomisin O, and four 1,4-bis(phenyl)-2,3-dimethylbutane type lignans, pregomisin, meso-dihydroguaiaretic acid, isoanwulignan, and sphenanlignan were isolated from the aerial parts of Schisandra propinqua var. propinqua.
CONCLUSIONS:
The structures of 1 and 2 were elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques.

Zhongguo Zhong Yao Za Zhi. 2001 Oct;26(10):694-7.

Studies on chemical constituents of Schisandra propinqua (Wall.) Hook. f. et Thoms.[Pubmed: 12776319]

To isolate and characterize compounds from the stems of Schisandra propinqua.
METHODS AND RESULTS:
Extracting with solvent, isolating by column chromatography and identifying by the spectroscopic methods. Six dibenzocyclooctadiene lignans were isolated and identified as tigloylgomisin P(1), angeloylgomisin O(2), Angeloylisogomisin O(3), kadsulignan L(4), (+/-) 5,8-epoxyl-6, 7-dimethyl-2',3',2",3"-dimethylenedioxy-4', 1"-dimethyl-1,2:3,4-dibenzo-1, 3-cyclooctadiene(5) and wuweizisu C(6).
CONCLUSIONS:
Compounds 4 and 5 were the first two dibenzocyclooctadiene lignans with an 6,9-epoxy bridge cycle discovered in the genus Schisandra. The others were originally isolated from S. propinqua.

Angeloylisogomisin O Dilution Calculator

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Preparing Stock Solutions of Angeloylisogomisin O

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0056 mL 10.0281 mL 20.0562 mL 40.1123 mL 50.1404 mL
5 mM 0.4011 mL 2.0056 mL 4.0112 mL 8.0225 mL 10.0281 mL
10 mM 0.2006 mL 1.0028 mL 2.0056 mL 4.0112 mL 5.014 mL
50 mM 0.0401 mL 0.2006 mL 0.4011 mL 0.8022 mL 1.0028 mL
100 mM 0.0201 mL 0.1003 mL 0.2006 mL 0.4011 mL 0.5014 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Angeloylisogomisin O

Lignans from Schisandra propinqua var. propinqua.[Pubmed:17666862]

Chem Pharm Bull (Tokyo). 2007 Aug;55(8):1281-3.

Two new dibenzocyclooctadiene lignans angeloyl-(+)-gomisin K(3) (1) and methylisogomisin O (2), together with six known ones, isogomisin O, Angeloylisogomisin O, gomisin O, angeloygomisin O, benzoylgomisin O, epigomisin O, and four 1,4-bis(phenyl)-2,3-dimethylbutane type lignans, pregomisin, meso-dihydroguaiaretic acid, isoanwulignan, and sphenanlignan were isolated from the aerial parts of Schisandra propinqua var. propinqua. The structures of 1 and 2 were elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques.

[Studies on chemical constituents of Schisandra propinqua (Wall.) Hook. f. et Thoms].[Pubmed:12776319]

Zhongguo Zhong Yao Za Zhi. 2001 Oct;26(10):694-7.

OBJECTIVE: To isolate and characterize compounds from the stems of Schisandra propinqua. METHOD: Extracting with solvent, isolating by column chromatography and identifying by the spectroscopic methods. RESULT: Six dibenzocyclooctadiene lignans were isolated and identified as tigloylgomisin P(1), angeloylgomisin O(2), Angeloylisogomisin O(3), kadsulignan L(4), (+/-) 5,8-epoxyl-6, 7-dimethyl-2',3',2",3"-dimethylenedioxy-4', 1"-dimethyl-1,2:3,4-dibenzo-1, 3-cyclooctadiene(5) and wuweizisu C(6). CONCLUSION: Compounds 4 and 5 were the first two dibenzocyclooctadiene lignans with an 6,9-epoxy bridge cycle discovered in the genus Schisandra. The others were originally isolated from S. propinqua.

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