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Schisanwilsonin I

CAS# 1181216-84-1

Schisanwilsonin I

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Product Name & Size Price Stock
Schisanwilsonin I: 5mg $638 In Stock
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Quality Control of Schisanwilsonin I

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Chemical structure

Schisanwilsonin I

3D structure

Chemical Properties of Schisanwilsonin I

Cas No. 1181216-84-1 SDF Download SDF
PubChem ID 21668973 Appearance Powder
Formula C28H34O9 M.Wt 514.6
Type of Compound Lignans Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC=C(C)C(=O)OC1C2=CC(=C(C(=C2C3=C(C4=C(C=C3CC(C1(C)O)C)OCO4)OC)OC)OC)OC
Standard InChIKey BKGUPIVDQHHVMV-OUJBPAAASA-N
Standard InChI InChI=1S/C28H34O9/c1-9-14(2)27(29)37-26-17-12-18(31-5)22(32-6)25(34-8)21(17)20-16(10-15(3)28(26,4)30)11-19-23(24(20)33-7)36-13-35-19/h9,11-12,15,26,30H,10,13H2,1-8H3/b14-9+/t15-,26-,28+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Schisanwilsonin I

The fruits of Schisandra wilsoniana

Biological Activity of Schisanwilsonin I

DescriptionSchisanwilsonin D, and schisantherin C show anti-HBV activity.
In vitro

Schisanwilsonins A–G and related anti-HBV lignans from the fruits of Schisandra wilsoniana.[Reference: WebLink]

Bioorganic & Medicinal Chemistry Letters,2009,19(17):4958-4962.


METHODS AND RESULTS:
Seven new dibenzocyclooctane lignans, schisanwilsonins A–G (1–7), were isolated from the fruits of Schisandra wilsoniana, together with five known lignans (8–12). The structures of these new compounds were elucidated by spectroscopic methods including 2D-NMR techniques. The 12 lignans were tested for anti-hepatitis B virus (HBV) activity in vitro.
CONCLUSIONS:
Schisanwilsonin D (4), schisantherin C (9), deoxyschizandrin (10) and (+)-gomisin K3 (11) showed anti-HBV activity. 9 exhibited the most potent anti-HBV activity with potency against HBsAg and HBeAg secretion by 59.7% and 34.7%, respectively, at 50 μg/mL.

Schisanwilsonin I Dilution Calculator

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Schisanwilsonin I Molarity Calculator

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Preparing Stock Solutions of Schisanwilsonin I

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9433 mL 9.7163 mL 19.4326 mL 38.8651 mL 48.5814 mL
5 mM 0.3887 mL 1.9433 mL 3.8865 mL 7.773 mL 9.7163 mL
10 mM 0.1943 mL 0.9716 mL 1.9433 mL 3.8865 mL 4.8581 mL
50 mM 0.0389 mL 0.1943 mL 0.3887 mL 0.7773 mL 0.9716 mL
100 mM 0.0194 mL 0.0972 mL 0.1943 mL 0.3887 mL 0.4858 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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