7-Hydroxy-3-(4-hydroxybenzyl)chromanCAS# 1180504-64-6 |
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| Cas No. | 1180504-64-6 | SDF | Download SDF |
| PubChem ID | 11708657 | Appearance | Powder |
| Formula | C16H16O3 | M.Wt | 256.3 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 3-[(4-hydroxyphenyl)methyl]-3,4-dihydro-2H-chromen-7-ol | ||
| SMILES | C1C(COC2=C1C=CC(=C2)O)CC3=CC=C(C=C3)O | ||
| Standard InChIKey | GXMQROMLTBPBKV-UHFFFAOYSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Dracaena cochinchinensis
| Description | 1. 7-Hydroxy-3-(4-hydroxybenzyl)chroman shows moderate inhibitory activity against a chymotrypsin-like activity of the proteasome. |
7-Hydroxy-3-(4-hydroxybenzyl)chroman Dilution Calculator
7-Hydroxy-3-(4-hydroxybenzyl)chroman Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.9017 mL | 19.5084 mL | 39.0168 mL | 78.0336 mL | 97.5419 mL |
| 5 mM | 0.7803 mL | 3.9017 mL | 7.8034 mL | 15.6067 mL | 19.5084 mL |
| 10 mM | 0.3902 mL | 1.9508 mL | 3.9017 mL | 7.8034 mL | 9.7542 mL |
| 50 mM | 0.078 mL | 0.3902 mL | 0.7803 mL | 1.5607 mL | 1.9508 mL |
| 100 mM | 0.039 mL | 0.1951 mL | 0.3902 mL | 0.7803 mL | 0.9754 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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7-hydroxy-3-(4-hydroxybenzyl)chroman and broussonin b: neurotrophic compounds, isolated from Anemarrhena asphodeloides BUNGE, function as proteasome inhibitors.[Pubmed:16141565]
Biol Pharm Bull. 2005 Sep;28(9):1798-800.
The extract of Anemarrhenae Rhizoma (rhizomes of Anemarrhena asphodeloides BUNGE) showed neurotrophic activity toward rat pheochromocytoma (PC-12) cells. Bioassay-guided purification afforded four compounds, 2,6,4'-trihydroxy-4-methoxybenzophenone (1), 7-Hydroxy-3-(4-hydroxybenzyl)chroman (2), broussonin B (3), and cis-hinokiresinol (4). Compounds 1-3 induced neurite outgrowth in PC-12 cells at concentration of 50 microg/ml, while 4 was less active. In addition, compounds 2-4 showed moderate inhibitory activities against a chymotrypsin-like activity of the proteasome.
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